Results 201 to 210 of about 5,624,280 (251)

Multidimensional Sustainability Assessment of Chemical Valorization Pathways for PET Waste: A Literature-Based Early-Design-Stage Index Including Technology Readiness. [PDF]

ACS Omega
Pulido-Peña DA, López Rojas L, Narváez-Rincón PC.   +2 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Antimicrobial resistance in wastewater-impacted coastal waters: implications for environmental surveillance and public health. [PDF]

Microbiology (Reading)
Cahill N, Kovarova A, Alfahl Z, O'Connor L, Morris D.   +4 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Global Sensitivity Analysis of Societal Resilience Using Shapley Values and Polynomial Chaos Expansion. [PDF]

Risk Anal
Montanari E, Galariotis I, Cappannini A, Mara T, Redecker C.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Occurrence data for habitat suitability modelling to support conservation planning in Latvia: species list, observations and ecogeographical variable selection. [PDF]

Biodivers Data J
Starka R, Rūsiņa S, Auniņa L, Balalaikins M, Butkeviča J, Cera I, Čakstiņa D, Čeirāns A, Gailis J, Liepiņa L, Leimanis I, Mežaka A, Moisejevs R, Ozols J, Pilāte D, Priedniece I, Riters R, Rubene B, Strazdiņa L, Šakele V, Vancāns A, Vērpēja V, Vintulis V, Župerka MA, Vinogradovs I, Auniņš A, Avotiņš A.   +26 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

From tracking data to ecologically grounded tactical indicators: a conceptual validation procedure for team invasion sports. [PDF]

Front Psychol
Gang Z, Zixuan L, Yong J.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source