Results 51 to 60 of about 272,251 (311)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Vibration Mitigation Effect Investigation of a New Slab Track Plate Design

Sensors, 2019
This study proposed a novel vibration mitigation slab track plate design to mitigate the vibration induced in urban rail transit operations. The optimal recipe for the newly designed slab track plate is obtained by a series of laboratory tests, and both ...
Linya Liu, Xuan Wang, Yun-Lai Zhou, Jialiang Qin   +3 more
doaj   +1 more source

Introduction to traffic noise abatement

, 2014
Presents Evidence-Based Guidance on Noise Abatement Methods Solutions for reducing the noise impact of road and rail traffic can be found in the use of natural elements in combination with artificial elements in urban and rural environments.
Kihlman, Tor, Tor Kihlman, Wolfgang Kropp, Forss\ue9n, Jens, Kropp, Wolfgang, Kihlman, Tor,, Kropp, Wolfgang,, Forssén, Jens,, Jens Forssén   +8 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Extremely low-frequency magnetic field exposure level for Koreans by occupational code

Emerging Contaminants, 2018
This study attempted to identify the level of exposure of 350 subjects to the extremely low-frequency magnetic field (ELF-MF). The occupational group showed significantly high levels of ELF-MF in every exposure indicator during work and transportation (p 
Joon Sig Jung, Mailan Arachchige Don Rajitha Kawshalya, In Keun Shim, Jung Min Ryu, Myung Hee Kwon, Duck Shin Park, Seung Cheol Hong   +6 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

ANASE: measuring aircraft noise annoyance very unreliably. [PDF]

, 2008
Does anyone who lives under a flight-path like aircraft noise? It is a political hot potato as well as a peace-destroyer. Tens of thousands of people will hear the noise from any third runway at Heathrow.
Brooker, Peter
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Deep learning-enhanced geospatial modeling for indoor radon mapping in Jeollabuk-do, South Korea

Geomatics, Natural Hazards & Risk
Radon (Rn-222) is a naturally occurring radioactive gas that poses significant lung cancer risks when accumulated indoors, making accurate predictions of its spatial distribution crucial for public health.
Saro Lee, Liadira Kusuma Widya, Jungsub Lee, Jongchun Lee, Bo Ram Park, Juhee Yoo, Woojin Lee   +6 more
doaj   +1 more source