Results 51 to 60 of about 1,014,437 (288)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Comparison of noise indicators in an urban context [PDF]

open access: yes, 2016
Inter-Noise 2016, 45th International Congress and Exposition of Noise Control Engineering, HAMBOURG, ALLEMAGNE, 21-/08/2016 - 24/08/2016Noise is a major environmental issue, which gave birth in the last decades to the development of many engineering ...
Aumond, Pierre   +6 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Negative Impact of Noise on Adolescents’ Executive Function: An Online Study in the Context of Home-Learning During a Pandemic

open access: yesFrontiers in Psychology, 2021
UNICEF estimates that 1.6 billion children across the world have had their education impacted by COVID-19 and have attempted to continue their learning at home. With ample evidence showing a negative impact of noise on academic achievement within schools,
Brittney Chere, Natasha Kirkham
doaj   +1 more source

Poor qubits make for rich physics: noise-induced quantum Zeno effects and noise-induced Berry phases

open access: yes, 2009
We briefly review three ways that environmental noise can slow-down (or speed-up) quantum transitions; (i) Lamb shifts, (ii) over-damping and (iii) orthogonality catastrophe.
Giovanni Basso   +2 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Vibration Mitigation Effect Investigation of a New Slab Track Plate Design

open access: yesSensors, 2019
This study proposed a novel vibration mitigation slab track plate design to mitigate the vibration induced in urban rail transit operations. The optimal recipe for the newly designed slab track plate is obtained by a series of laboratory tests, and both ...
Linya Liu   +3 more
doaj   +1 more source

Environmental Noise and Nonlinear Relaxation in Biological Systems [PDF]

open access: yes, 2011
We analyse the effects of environmental noise in three different biological systems: (i) mating behaviour of individuals of \emph{Nezara viridula} (L.) (Heteroptera Pentatomidae); (ii) polymer translocation in crowded solution; (iii) an ecosystem ...
Adorno, D. Persano   +10 more
core   +1 more source

Dispersal and noise: Various modes of synchrony in\ud ecological oscillators [PDF]

open access: yes, 2012
We use the theory of noise-induced phase synchronization to analyze the effects of dispersal on the synchronization of a pair of predator-prey systems within a fluctuating environment (Moran effect). Assuming that each isolated local population acts as a
Bressloff, P. C., Lai, Y. M.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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