Results 71 to 80 of about 5,880,845 (298)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Experimental Study on the Rail Damper for Vibration and Noise Control and Rail Corrugation Suppression

Urban Rail Transit
With the rapid construction of rail transportation infrastructure, vibration issues caused by wheel–rail interactions during train operation have become a significant concern.
Fangqiu Sun, Zhiqiang Sun, Ruihua Liang, Deyun Ding, Meng Ma   +4 more
doaj   +1 more source

Environmental noise and annoyance in adults: Research in central, eastern and south-eastern Europe and newly independent states

Noise and Health, 2013
Research work on the adverse effects of noise on annoyance in adults is well documented in Western Europe, but there is a knowledge gap concerning this type of research in Central and Eastern Europe (CEE), South-East Europe (SEE), and Newly Independent ...
Jurgita Lekaviciute, Lubica Argalasova-Sobotova   +1 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Amplifying concerns: An exploration of community noise levels in rural communities impacted by wood pellet production

Environmental Challenges
Wood pellets are increasingly promoted as a renewable and sustainable energy source, driving the global wood pellet market to a projected value of $16 billion by 2026. However, the rapid expansion of this industry disproportionately affects predominantly
E.D. Walker, N. Franzen Lee, C. Nica, A. Barnes, B. Graham, K. Martin   +5 more
doaj   +1 more source

Environmental noise exposure. [PDF]

Environmental Health Perspectives, 1998
Passchier-Vermeer, W., Passchier, W.
openaire   +2 more sources

Tourist Influence on Nightlife Noise [PDF]

, 2010
Although environmental noise from entertainment and leisure activities is causing a growing number of complaints from EU population, this noise issue is not covered by the current EU initiatives on environmental noise management.
Ausejo Prieto, Miguel, Recuero López, Manuel, Pavón García, Ignacio, Asensio Rivera, César   +3 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Revision of Swiss noise exposure limits in the wake of the WHO environmental noise guidelines: methodology matters

, 2020
The current concept for the protection of the population against noise in Switzerland was defined in the 1980s in the Environmental Protection Act and subsequently substantiated with exposure limit values.
Thomann, Georg (author), Röösli, Martin (author), Wunderli, Jean Marc (author), Brink, Mark (author), Artho, Jürg (author), Boegli, Hans (author), Walker, Urs (author)   +6 more
core   +1 more source