Results 81 to 90 of about 6,139,731 (299)

Preparation of guidance for health risk assessment of environmental noise

open access: yes, 2010
Evidence has accumulated regarding health effects of environmental noise. The WHO European Centre for Environment and Health, Bonn, has organized several meetings of experts over recent years to examine the current state of knowledge, and to further ...
Brown, AL   +4 more
core  

Tyre/road noise annoyance assessment through virtual sounds [PDF]

open access: yes, 2016
Road-traffic noise is the most significant source of environmental noise. Among the several different sources of noise emission from vehicles, tyre/road noise at speeds above 40 km/h is the most prevalent.
Francisco Soares   +11 more
core   +1 more source

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

open access: yesParticle and Fibre Toxicology, 2018
Background Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD), and may contribute to endothelial dysfunction and development of atherosclerosis. It
Bendik C. Brinchmann   +15 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Revision of Swiss noise exposure limits in the wake of the WHO environmental noise guidelines: methodology matters

open access: yes, 2020
The current concept for the protection of the population against noise in Switzerland was defined in the 1980s in the Environmental Protection Act and subsequently substantiated with exposure limit values.
Thomann, Georg (author)   +6 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Experimental Study on the Rail Damper for Vibration and Noise Control and Rail Corrugation Suppression

open access: yesUrban Rail Transit
With the rapid construction of rail transportation infrastructure, vibration issues caused by wheel–rail interactions during train operation have become a significant concern.
Fangqiu Sun   +4 more
doaj   +1 more source

Environmental noise and annoyance in adults: Research in central, eastern and south-eastern Europe and newly independent states

open access: yesNoise and Health, 2013
Research work on the adverse effects of noise on annoyance in adults is well documented in Western Europe, but there is a knowledge gap concerning this type of research in Central and Eastern Europe (CEE), South-East Europe (SEE), and Newly Independent ...
Jurgita Lekaviciute   +1 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

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