Results 81 to 90 of about 5,880,845 (298)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Evaluation of the effect of wheel tread condition on the dynamic response of PC sleepers

open access: yesNihon Kikai Gakkai ronbunshu
Prestressed concrete sleepers (PC sleepers) are an important component of railway tracks. The dynamic response of PC sleepers to passing trains is influenced by various factors relating to the vehicles and tracks. However, few studies have quantitatively
Keiichi GOTO   +5 more
doaj   +1 more source

Hegselmann–Krause model with environmental noise

open access: yesTransactions of the American Mathematical Society
We study a continuous-time version of the Hegselmann–Krause model describing the opinion dynamics of interacting agents subject to random perturbations. Mathematically speaking, the opinion of agents is modelled by an interacting particle system with a non-Lipschitz continuous interaction force, perturbed by idiosyncratic and environmental noises ...
Chen, Li   +2 more
openaire   +3 more sources

Introduction to traffic noise abatement

open access: yes, 2014
Presents Evidence-Based Guidance on Noise Abatement Methods Solutions for reducing the noise impact of road and rail traffic can be found in the use of natural elements in combination with artificial elements in urban and rural environments.
Kihlman, Tor   +8 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Information on levels of environmental noise requisite to protect public health and welfare with an adequate margin of safety

open access: yes, 2020
INFORMATION ON LEVELS OF ENVIRONMENTAL NOISE REQUISITE TO PROTECT PUBLIC HEALTH AND WELFARE WITH AN ADEQUATE MARGIN OF SAFETY 1~ARCH 1974 PREPARED BY THE U.S.
United States. Office of Noise Abatement and Control;
core  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

LIFE Monza: comparison between ante and post-operam noise and air quality monitoring activities in a Noise Low Emission Zone

open access: yesNoise Mapping, 2020
LIFE MONZA project (Methodologies fOr Noise low emission Zones introduction And management) aims at defining an easy-replicable method for the identification and management of the Noise Low Emission Zones (Noise LEZ), urban areas subject to traffic ...
Silvaggio Rosalba   +18 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

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