Results 61 to 70 of about 6,139,731 (299)

The Negative Impact of Noise on Adolescents’ Executive Function: An Online Study in the Context of Home-Learning During a Pandemic

Frontiers in Psychology, 2021
UNICEF estimates that 1.6 billion children across the world have had their education impacted by COVID-19 and have attempted to continue their learning at home. With ample evidence showing a negative impact of noise on academic achievement within schools,
Brittney Chere, Natasha Kirkham
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Tourist Influence on Nightlife Noise [PDF]

, 2010
Although environmental noise from entertainment and leisure activities is causing a growing number of complaints from EU population, this noise issue is not covered by the current EU initiatives on environmental noise management.
Ausejo Prieto, Miguel, Recuero López, Manuel, Pavón García, Ignacio, Asensio Rivera, César   +3 more
core  

Health aspects associated with wind turbine noise : Results from three field studies [PDF]

, 2011
Wind farms are a new source of environmental noise. The impact of wind turbine noise on health and well-being has not yet been well-established and remains under debate.
Pedersen, Eja, Eja Pedersen, Pedersen, Eja,   +2 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Development of an open-source road traffic noise model for exposure assessment [PDF]

, 2014
This paper describes the development of a model for assessing TRAffic Noise EXposure (TRANEX) in an open-source geographic information system. Instead of using proprietary software we developed our own model for two main reasons: 1) so that the treatment
Beevers, Sean, Kelly, Frank J., Fecht, Daniela, Gulliver, John, Bell, Margaret, Fabbri, Federico, Dajnak, David, Vienneau, Danielle, Morley, David, Kelly, Frank; id_orcid, Goodman, Paul, Vienneau, D, Fecht, D, Gulliver, J, Bell, M, Morley, D, Beevers, S, Dajnak, D, Goodman, P, Kelly, FJ, Fabbri, F   +20 more
core   +1 more source

Environmental noise in hospitals: a systematic review

, 2021
Environmental noise has been growing in recent years, causing numerous health problems. Highly sensitive environments such as hospitals deserve special attention, since noise can aggravate patients’ health issues and impair the performance of healthcare ...
de Lima, Eligelcy Augusta [UNESP], Martins, Antônio Cesar Germano [UNESP], da Cunha e Silva, Darllan Collins [UNESP], Zannin, Paulo Henrique Trombetta, de Oliveira, Renan Angrizani [UNESP], de Lima Andrade, Erik [UNESP], Antônio Cesar Germano Martins, Renan Angrizani de Oliveira, Eligelcy Augusta de Lima, Erik de Lima Andrade, Darllan Collins da Cunha e Silva, Paulo Henrique Trombetta Zannin   +11 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Extremely low-frequency magnetic field exposure level for Koreans by occupational code

Emerging Contaminants, 2018
This study attempted to identify the level of exposure of 350 subjects to the extremely low-frequency magnetic field (ELF-MF). The occupational group showed significantly high levels of ELF-MF in every exposure indicator during work and transportation (p 
Joon Sig Jung, Mailan Arachchige Don Rajitha Kawshalya, In Keun Shim, Jung Min Ryu, Myung Hee Kwon, Duck Shin Park, Seung Cheol Hong   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source