Results 101 to 110 of about 13,359,027 (313)

Sleep disruption with aging in senescence-accelerated mice-prone 8 (SAMP8) mice and analysis of factors associated with age-related sleep fragmentation using RNA sequencing of the hypothalamus

Neurobiology of Sleep and Circadian Rhythms
Aging is a risk factor for various disorders, and age-dependent changes in sleep parameters are involved in the pathogenesis of many diseases. Senescence-accelerated mice-prone 8 (SAMP8) have a short lifespan and show a disrupted circadian rhythm ...
Kazuyuki Okamura, Rie Yanagisawa, Miyuki Sato, Takehiro Suzuki, Nobuyoshi Nakajima, Tin-Tin Win-shwe, Eiko Koike   +6 more
doaj   +1 more source

Characteristics of PM10 Chemical Source Profiles for Geological Dust from the South-West Region of China

Atmosphere, 2016
Ninety-six particulate matter (PM10) chemical source profiles for geological sources in typical cities of southwest China were acquired from Source Profile Shared Service in China. Twenty-six elements (Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu,
Yayong Liu, Wenjie Zhang, Zhipeng Bai, Wen Yang, Xueyan Zhao, Bin Han, Xinhua Wang   +6 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Deconstructing Vulnerability for Psychosis: Meta-Analysis of Environmental Risk Factors for Psychosis in Subjects at Ultra High-Risk

European psychiatry, 2017
Background Subjects at ultra high-risk (UHR) for psychosis have an enhanced vulnerability to develop the disorder but the risk factors accounting for this accrued risk are undetermined.
P. Fusar-Poli, M. Tantardini, S. Simone, V. Ramella-Cravaro, D. Oliver, J. Kingdon, M. Kotlicka‐Antczak, L. Valmaggia, J. Lee, M. Millan, S. Galderisi, U. Balottin, V. Ricca, P. McGuire   +13 more
semanticscholar   +1 more source

Home Environmental Health Risks

OJIN: The Online Journal of Issues in Nursing, 2007
Home environmental health risks and the pollution of indoor residential air are becoming increasingly recognized as sources of injury and exacerbation of illness, particularly in vulnerable populations such as pregnant women, infants, children, the elderly, and those living with a chronic medical condition or disability.
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Pollution Characteristics, Toxicological Properties, and Health Risk Assessment of Phthalic Acid Esters in Water, Soil, and Atmosphere

Atmosphere
Phthalic acid esters (PAEs) are a class of common environmental endocrine disruptors (EEDs), capable of causing considerable pollution to water, soil, and air and producing a range of adverse health impacts in humans.
Fangyun Long, Yanqin Ren, Yuanyuan Ji, Junling Li, Haijie Zhang, Zhenhai Wu, Rui Gao, Fang Bi, Zhengyang Liu, Hong Li   +9 more
doaj   +1 more source

Environmental risk factors of type 2 diabetes—an exposome approach

Diabetologia, 2021
J. Beulens, M. Pinho, T. Abreu, N. D. den Braver, T. Lam, A. Huss, J. Vlaanderen, Tabea S. Sonnenschein, Noreen Z. Siddiqui, Zhendong Yuan, J. Kerckhoffs, A. Zhernakova, Milla F. Brandao Gois, Roel C. H. Vermeulen   +13 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Toxicological Effects and Health Impacts of Per- and Polyfluoroalkyl Substances (PFAS) in Humans

Toxics
Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals notable for their high persistence and extensive applications. With the advancement of detection technologies in recent years, PFAS have been frequently identified in ...
Jie Ma, Ge Gao, Bitan Meng, Xinni Wei, Long Zhao, Zaiming Ge   +5 more
doaj   +1 more source