Results 51 to 60 of about 1,490,052 (312)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Exploring HONO production from particulate nitrate photolysis in representative regions of China: characteristics, influencing factors, and environmental implications [PDF]

Atmospheric Chemistry and Physics
The production mechanism of atmospheric nitrous acid (HONO), an important precursor of the hydroxyl radical (OH), remains controversial. Few studies have explored the effects of particulate nitrate photolysis on HONO sources under different environment ...
B. Li, J. Gao, C. Chen, L. Wen, Y. Zhang, J. Li, Y. Zhang, X. Du, K. Zhang, J. Wang   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A novel approach for indentifying uncertainties within environmental risk assessments [PDF]

, 2012
Appendices held on CD-RomUncertainties can manifest within the different aspects of environmental risk assessments, affecting the validity of the risk estimate and, in turn, weakening the basis for risk management actions.
Skinner, Daniel J. C.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Restoration of aquatic vegetation can mitigate the risk of eutrophication in large shallow lakes

Scientific Reports
The role of aquatic vegetation restoration in mitigating lake eutrophication is well-recognized, yet the underlying nutrient dynamics-vegetation response relationship remains poorly quantified, hindering a mechanistic understanding of grass-algae regime ...
Xiang Li, Rui Xia, Zhongwen Yang, Yan Chen, Chao Yan, Junde Ming, Qiang Hu, Hao Liu   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Methane emissions from riverine ecosystems in the Yangtze River basin are driven by ebullition rather than diffusion

Communications Earth & Environment
Quantifying methane emissions from riverine ecosystems is crucial for optimizing greenhouse gas control strategies. However, partitioning methane emissions between diffusion and ebullition pathways remains insufficiently investigated.
Xiuyuan Chen, Fuhong Sun, Jiayue Li, Ziteng Wang, Yiding Guo, Nannan Huang, Qianyu Zhao, Fengchang Wu   +7 more
doaj   +1 more source

Pollution Characteristics and Health Risk Assessment of Summertime Atmospheric Volatile Halogenated Hydrocarbons in a Typical Urban Area of Beijing, China

Atmosphere, 2020
Twenty-three atmospheric volatile halogenated hydrocarbons (VHHs) were detected in a typical urban area of Beijing, China from 24 August to 4 September, 2012. The mean and range in daily mass concentrations of the 23 VHHs were 30.53 and 13.45–76.33 µg/m3,
Yuanyuan Ji, Linghong Xu, Hong Li, Chuhan Wang, Dongyao Xu, Lei Li, Hao Zhang, Jingchun Duan, Yujie Zhang, Xuezhong Wang, Weiqi Zhang, Fang Bi, Yizhen Chen, Yanting Yu, Lingshuo Meng   +14 more
doaj   +1 more source