Results 71 to 80 of about 13,359,027 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Restoration of aquatic vegetation can mitigate the risk of eutrophication in large shallow lakes

Scientific Reports
The role of aquatic vegetation restoration in mitigating lake eutrophication is well-recognized, yet the underlying nutrient dynamics-vegetation response relationship remains poorly quantified, hindering a mechanistic understanding of grass-algae regime ...
Xiang Li, Rui Xia, Zhongwen Yang, Yan Chen, Chao Yan, Junde Ming, Qiang Hu, Hao Liu   +7 more
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Codon usage bias is presumably affected by tRNA selection effects in Actinidia polyploidization events

BMC Genomics
Background Polyploidization is one of the main mechanisms in speciation, yet its effects on the frequency and distribution of synonymous codons remain unclear, which may lead to distinct patterns of codon usage bias (CUB) in polyploid species.
Yi Zhou, Zhilu Sheng, Dongbin Li, Wencui Li, Yujia Peng, Zhaopeng Song, Zhanjun Quan, Yongbo Liu   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Methane emissions from riverine ecosystems in the Yangtze River basin are driven by ebullition rather than diffusion

Communications Earth & Environment
Quantifying methane emissions from riverine ecosystems is crucial for optimizing greenhouse gas control strategies. However, partitioning methane emissions between diffusion and ebullition pathways remains insufficiently investigated.
Xiuyuan Chen, Fuhong Sun, Jiayue Li, Ziteng Wang, Yiding Guo, Nannan Huang, Qianyu Zhao, Fengchang Wu   +7 more
doaj   +1 more source

Toward the Development and Application of an Environmental Risk Assessment Framework for Microplastic

Environmental Toxicology and Chemistry, 2019
Emissions of plastic waste to the environment and the subsequent degradation into microplastic particles that have the potential to interact with biological organisms represent a concern for global society.
T. Gouin, R. Becker, A.-G. Collot, John W. Davis, Brett Howard, K. Inawaka, M. Lampi, B. S. Ramón, Jay Shi, Philipp W. Hopp   +9 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source