Results 31 to 40 of about 502,413 (242)

Revealing population demographics with environmental RNA

Molecular Ecology Resources
The analyses of environmental DNA (eDNA) and environmental RNA (eRNA) released by organisms into their surrounding environment (water, soil and air) have emerged as powerful tools for monitoring biodiversity. While eDNA has been widely adopted for the non‐invasive detection of species and characterization of community composition, the utilization of ...
Robert Hechler, Melania Cristescu
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors [PDF]

Scientific Data, 2016
AbstractThe full exploration of gene-environment interactions requires model organisms with well-characterized ecological interactions in their natural environment, manipulability in the laboratory and genomic tools. The waterfleaDaphnia magnais an established ecological and toxicological model species, central to the food webs of freshwater lentic ...
Orsini, Luisa, Gilbert, Donald, Podicheti, Ram, Jansen, Mieke, Brown, James B., Solari, Omid Shams, Spanier, Katina, Colbourne, John K., Rush, Douglas, Decaestecker, Ellen, Asselman, Jana, De Schamphelaere, Karel A.C., Ebert, Dieter, Haag, Christoph R., Kvist, Jouni, Laforsch, Christian, Petrusek, Adam, Beckerman, Andrew P., Little, Tom J., Chaturvedi, Anurag, Pfrender, Michael E., De Meester, Luc, Frilander, Mikko J.   +22 more
openaire   +11 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A’s impact on ERα-mediated transcriptional bursting

iScience
Summary: Transcription initiation at hormone-responsive gene promoters involves recruitment of numerous proteins that initiate stochastic events known as transcriptional bursts.
Christopher R. Day, Pelin Yaşar, Gloria Adedoyin, Brian D. Bennett, Carson C. Chow, Joseph Rodriguez   +5 more
doaj   +1 more source

Environmental RNA degrades more rapidly than environmental DNA across a broad range of pH conditions

Molecular Ecology Resources, 2022
AbstractAlthough the use and development of molecular biomonitoring tools based on environmental nucleic acids (eDNA and eRNA; collectively known as eNAs) have gained broad interest for the quantification of biodiversity in natural ecosystems, studies investigating the impact of site‐specific physicochemical parameters on eNA‐based detection methods ...
Kaushar Kagzi, Robert M. Hechler, Gregor F. Fussmann, Melania E. Cristescu   +3 more
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Poly(A) tail regulation in stem cells and early development

Cell Regeneration
Eukaryotic mRNAs are polyadenylated at their 3’-ends, and the poly(A) tails play critical roles in post-transcriptional gene regulation by influencing mRNA stability and translation.
Xiaosu Miao, Guang Hu
doaj   +1 more source

Methodological considerations for aqueous environmental RNA collection, preservation, and extraction

Analytical Sciences, 2023
Environmental RNA (eRNA) analysis is expected to infer species' physiological information (health status, developmental stage, and environmental stress response) and their distribution and composition more correctly than environmental DNA (eDNA) analysis.
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source