Results 41 to 50 of about 892,996 (295)

Environmentally-Induced Transgenerational Epigenetic Inheritance: Implication of PIWI Interacting RNAs [PDF]

Cells, 2019
Environmentally-induced transgenerational epigenetic inheritance is an emerging field. The understanding of associated epigenetic mechanisms is currently in progress with open questions still remaining. In this review, we present an overview of the knowledge of environmentally-induced transgenerational inheritance and associated epigenetic mechanisms ...
Karine Casier, Antoine Boivin, Clément Carré, Laure Teysset   +3 more
openaire   +4 more sources

A Path to Implement Precision Child Health Cardiovascular Medicine. [PDF]

, 2017
Congenital heart defects (CHDs) affect approximately 1% of live births and are a major source of childhood morbidity and mortality even in countries with advanced healthcare systems. Along with phenotypic heterogeneity, the underlying etiology of CHDs is
Brian Reemtsen, J. Paul Finn, Juan Alejos, Marlin Touma, Marlin Touma, Nancy Halnon, Stanley F. Nelson, Yibin Wang, Yibin Wang   +8 more
core   +2 more sources

Evidence-based Decision-making in Canada’s Protected Areas Organizations: Implications for Management Effectiveness [PDF]

, 2018
Aichi Biodiversity Target 19 calls on Parties to the United Nations Convention on Biological Diversity (CBD) to improve, share, transfer, and apply knowledge.
Beechey, Thomas J., Bocking, Stephen, Groulx, Mark W., Lemieux, Christopher J.   +3 more
core   +2 more sources

Unravelling the active microbial community in a thermophilic anaerobic digester-microbial electrolysis cell coupled system under different conditions [PDF]

, 2017
Thermophilic anaerobic digestion (AD) of pig slurry coupled to a microbial electrolysis cell (MEC) with a recirculation loop was studied at lab-scale as a strategy to increase AD stability when submitted to organic and nitrogen overloads.
Bonmatí Blasi, August, Cerrillo Moreno, Míriam, Viñas Canals, Marc   +2 more
core   +2 more sources

Environmental change exposes beneficial epistatic interactions in a catalytic RNA [PDF]

Proceedings of the Royal Society B: Biological Sciences, 2012
Natural selection drives populations of individuals towards local peaks in a fitness landscape. These peaks are created by the interactions between individual mutations. Fitness landscapes may change as an environment changes. In a previous contribution, we discovered a variant of the Azoarcus group I ribozyme that ...
Hayden Eric, Wagner Andreas
openaire   +3 more sources

Revealing population demographics with environmental RNA

Molecular Ecology Resources
The analyses of environmental DNA (eDNA) and environmental RNA (eRNA) released by organisms into their surrounding environment (water, soil and air) have emerged as powerful tools for monitoring biodiversity. While eDNA has been widely adopted for the non‐invasive detection of species and characterization of community composition, the utilization of ...
Robert Hechler, Melania Cristescu
openaire   +2 more sources

Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]

, 2016
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
A Ellahi, A Pidoux, A Selmecki, aF Straight, BD Strahl, C Ketel, C Li, C Trapnell, Ca Froyd, CJ Merrick, D Kadosh, DE Gottschling, GD Shankaranarayana, H Chibana, H Chibana, J Haran, J Huang, J Huang, J Nakayama, J Pérez-Martín, J Wendland, JC Tanny, JS Smith, Ka Morano, KR Hansen, L Vasiljeva, LH Freitas-Junior, LN Rusche, M Bryk, M Bühler, M Dubarry, M Paschini, M Van het Hoog, MA Pfaller, MD De Backer, MJ McEachern, N Saksouk, PA Dumesic, PR Lephart, PR Lephart, R Kaur, RB Wilson, RJ Bennett, S Greiss, S Henikoff, S Imai, S Kueng, S Rea, SI Iwaguchi, T Jones, T Kobayashi, T Kobayashi, T Kouzarides, VM Bruno, W Shou, WS Chu, X Bi   +56 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors [PDF]

Scientific Data, 2016
AbstractThe full exploration of gene-environment interactions requires model organisms with well-characterized ecological interactions in their natural environment, manipulability in the laboratory and genomic tools. The waterfleaDaphnia magnais an established ecological and toxicological model species, central to the food webs of freshwater lentic ...
Orsini, Luisa, Gilbert, Donald, Podicheti, Ram, Jansen, Mieke, Brown, James B., Solari, Omid Shams, Spanier, Katina, Colbourne, John K., Rush, Douglas, Decaestecker, Ellen, Asselman, Jana, De Schamphelaere, Karel A.C., Ebert, Dieter, Haag, Christoph R., Kvist, Jouni, Laforsch, Christian, Petrusek, Adam, Beckerman, Andrew P., Little, Tom J., Chaturvedi, Anurag, Pfrender, Michael E., De Meester, Luc, Frilander, Mikko J.   +22 more
openaire   +11 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source