Results 71 to 80 of about 1,427,250 (299)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Pharmaceuticals in the blubber of live free-swimming common bottlenose dolphins (Tursiops truncatus)
iScienceSummary: Pharmaceuticals prevent and treat diseases, yet inappropriate intake can result in harmful effects including mortality. Contaminants have become recurrent public and wildlife health concerns.
Anya Isabelle Ocampos +6 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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The process of developing distributed-efficacy and social practice in the context of ‘ending AIDS’
The Journal for Transdisciplinary Research in Southern Africa, 2015 Introduction: this article reflects on data that emanated from a programme evaluation and focuses on a concept we label ‘distributed-efficacy’. We argue that the process of developing and sustaining ‘distributed-efficacy’ is complex and indeterminate ...
Christopher Burman +4 more
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
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JPAIR Institutional Research Journal, 2013 The teaching of biodiversity conservation in the university level is a laudable effort of teachers. The study ascertained the environmental awareness, literacy and biodiversity conservation practices of college freshmen students in Bukidnon State ...
Lynnette Ejem, Alwielland Bello
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Predictors of oil shocks. Econophysical approach in environmental science
, 2021 Andrii Bielinskyi +7 more
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
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A Special Issue: Geomathematics in practice: Case studies from earth- and environmental sciences – Proceedings of the Croatian-Hungarian Geomathematical Congress, Hungary 2015 [PDF]
, 2016 István Gábor Hatvani, Janina Horváth
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