Results 111 to 120 of about 9,766,647 (363)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Protocol for estimating exposure to compound heat wave and ozone pollution under future climate change

open access: yesSTAR Protocols, 2023
Summary: Here we describe the procedure for estimating exposure to the compound heatwave and ozone pollution under future climate scenarios. We first apply the daily-level temperature and ozone concentration across the world and perform bias correction ...
Kailai Lu   +3 more
doaj  

Understanding leadership in the environmental sciences

open access: yes, 2015
Leadership is often assumed, intuitively, to be an important driver of sustainable development. To understand how leadership is conceptualized and analyzed in the environmental sciences and to discover what this research says about leadership outcomes ...
L. Evans   +5 more
semanticscholar   +1 more source

Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward

open access: yesToxicological Sciences, 2015
Neurotoxicity has been linked to a number of common drugs and chemicals, yet efficient and accurate methods to detect it are lacking. There is a need for more sensitive and specific biomarkers of neurotoxicity that can help diagnose and predict ...
Ruth Roberts   +15 more
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

iMESc – an interactive machine learning app for environmental sciences

open access: yesFrontiers in Environmental Science
As environmental sciences increasingly rely on complex datasets, machine learning (ML) has become crucial for identifying patterns and relationships. However, the integration of ML into workflows can pose challenges due to technical barriers or the time ...
Danilo Cândido Vieira   +4 more
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Editorial: Current Research on Soil Science and Related Aspects of Environmental Sciences in Galicia

open access: yesSpanish Journal of Soil Science, 2023
Avelino Núñez-Delgado   +2 more
doaj   +1 more source

Environmental Sciences [PDF]

open access: yes, 1994
Informational booklet describing the Environmental Sciences program at the Virginia Institute of Marine Science.
College of William and Mary, School of Marine Science, Virginia Institute of Marine Science
core   +1 more source

Science and environmental stewardship

open access: yesGlobal Bioethics, 2014
People’s vision of world phenomena is still based on the traditional mechanistic concept, which implies that process outcomes can be fully predicted and controlled. The new scientific concept that our world is characterized by complex, self-organizing processes, is so far acknowledged by few insiders.
openaire   +3 more sources

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