Results 111 to 120 of about 12,186,927 (332)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

AIMES: an enhanced monitoring system for environmental suitability of Aedes-borne diseases

Environmental Research Letters
Aedes -borne diseases, such as dengue, Zika, and chikungunya, pose a significant threat to millions of people worldwide each year. Considering the relationships between the emergence of these diseases and anthropogenic climate change, it has become ...
Javier Corvillo, Verónica Torralba, Carmen González Romero, Alba Llabrés-Brustenga, Núria Pérez-Zanón, Ana Riviére-Cinnamond, Ángel G Muñoz   +6 more
doaj   +1 more source

How the Marsden Fund has failed to achieve its full potential in the ESA panel: evidence of limitations in scope, biased outcomes, and futile applications [PDF]

, 2014
We have analysed the scope of proposals funded by the ‘Earth Sciences and Astronomy’ (ESA) panel of the Marsden Fund for the period 2004 to 2013.
Bryan, Karin R., Lowe, David J.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Corrigendum: BIIGLE 2.0 - Browsing and Annotating Large Marine Image Collections

Frontiers in Marine Science, 2020
Daniel Langenkämper, Martin Zurowietz, Timm Schoening, Tim W. Nattkemper   +3 more
doaj   +1 more source

Protocol for constructing an accessible exposure chamber for in vitro and in vivo modeling of airway environmental exposures

STAR Protocols
Summary: Exposure systems to study the effects of environmental exposures can be costly to purchase and difficult to use. Here, we present an accessible and cost-effective approach to building an exposure chamber in the lab.
Abdo Durra, Caroline Cherry, Coline Luo, Emily Huo, Isabella Passamano, Kristen Castillo, Andrew J. Lund, Woosuk Choi, Chandani Sen, Rachana Chandran, Tammy M. Rickabaugh, Brigitte N. Gomperts   +11 more
doaj   +1 more source

Elucidating Best Geospatial Estimation Method Applied to Environmental Sciences. [PDF]

Bull Environ Contam Toxicol, 2023
de Lourdes Berrios Cintrón M, Broomandi P, Cárdenas-Escudero J, Cáceres JO, Galán-Madruga D.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Tabular strategies for metadata in ecology, evolution, and the environmental sciences. [PDF]

Ecol Evol, 2022
Lortie CJ, Vargas Poulsen C, Brun J, Kui L.   +3 more
europepmc   +1 more source