Results 111 to 120 of about 1,541,248 (268)

The disconnect between researcher ambitions and reality in achieving impact in the Earth & Environmental Sciences - author survey. [PDF]

F1000Res, 2021
Kelly A, Gardner V, Gilbert A.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Protocol for assessing neighborhood physical disorder using the YOLOv8 deep learning model

STAR Protocols
Summary: Neighborhood physical disorder (PD), characterized by disruptions and irregularities in spatial elements, is associated with negative economic, social, and public health outcomes. Here, we present a protocol to quantitatively assess PD utilizing
Yan Li, Yue Ma, Ying Long
doaj   +1 more source

Plastic pollution as a canvas for change: fostering collaboration for environmental solutions and actions through art and science [PDF]

Jennifer L. Lavers, Alexander L. Bond
openalex   +1 more source

Curriculum Design of Chemical Knowledge in Courses of Environmental Geotechnical and Ecological Protection for New Agricultural Sciences [PDF]

, 2022
Lizhu Zhang, Aihua Wen, Aiping Tang, Fan Feng   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Protocol for establishing a map of mangrove species distribution using multispectral unmanned aerial vehicle data

STAR Protocols
Summary: Unmanned aerial vehicle (UAV) or drone image data are useful tools for creating machine learning-based mangrove categorization maps. Here, we present a protocol for creating a taxonomy map of mangrove species using machine learning and ...
Dung Trung Ngo, Hieu Huu Viet Nguyen, Binh Thi Thanh Nguyen, Ngoc Thi Dang   +3 more
doaj   +1 more source

Microbial World: Recent Developments in Health, Agriculture and Environmental Sciences: An Annual Conference Organized by Association of Microbiologists of India and Indian Network for Soil Contamination Research. [PDF]

Indian J Microbiol, 2021
Dhingra GG, Saxena A, Nigam A, Hira P, Singhvi N, Anand S, Kaur J, Kaur J, Dua A, Negi V, Gupta V, Sood U, Kumar R, Lal S, Verma H, Verma M, Singh P, Rawat CD, Tripathi C, Talwar C, Nagar S, Mahato NK, Prakash O, Singh M, Kuhad RC, Singh Y, Lal B, Pabbi S, Singh N, Kalia VC, Lal R.   +30 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

AI and climate resilience governance

iScience
Summary: While artificial intelligence (AI) offers promising solutions to address climate change impacts, it also raises many application limitations and challenges.
Sara Mehryar, Vahid Yazdanpanah, Jeffrey Tong   +2 more
doaj   +1 more source