Results 111 to 120 of about 1,477,177 (315)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Protocol for assessing neighborhood physical disorder using the YOLOv8 deep learning model

open access: yesSTAR Protocols
Summary: Neighborhood physical disorder (PD), characterized by disruptions and irregularities in spatial elements, is associated with negative economic, social, and public health outcomes. Here, we present a protocol to quantitatively assess PD utilizing
Yan Li, Yue Ma, Ying Long
doaj   +1 more source

The Bibliometric Literature on Scopus and WoS: The Medicine and Environmental Sciences Categories as Case of Study. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Cascajares M   +3 more
europepmc   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Protocol for establishing a map of mangrove species distribution using multispectral unmanned aerial vehicle data

open access: yesSTAR Protocols
Summary: Unmanned aerial vehicle (UAV) or drone image data are useful tools for creating machine learning-based mangrove categorization maps. Here, we present a protocol for creating a taxonomy map of mangrove species using machine learning and ...
Dung Trung Ngo   +3 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

AI and climate resilience governance

open access: yesiScience
Summary: While artificial intelligence (AI) offers promising solutions to address climate change impacts, it also raises many application limitations and challenges.
Sara Mehryar   +2 more
doaj   +1 more source

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