Results 111 to 120 of about 4,106,632 (313)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Oil and Water Don't Mix: Risk on Tap in Western Siberia [PDF]

open access: yes
In common with other areas throughout the Russian Federation, western Siberia faces formidable environmental pollution, a problem that in part is the legacy of the highly centralized Soviet era when meeting production quotas was the raison d'être for ...
Wernstedt, Kris
core  

Scientometric dimensions of technical reports from Bhabha Atomic Research Centre [PDF]

open access: yes, 2002
Technical report is one of the media to record the scientific information generated by scientists and engineers, Bhabha Atomic Research Centre (BARC) published 554 technical reports during 1990-99 under the categories: External (373) and Internal (181 ...
Kalyane, V. L.   +2 more
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Protocol for constructing an accessible exposure chamber for in vitro and in vivo modeling of airway environmental exposures

open access: yesSTAR Protocols
Summary: Exposure systems to study the effects of environmental exposures can be costly to purchase and difficult to use. Here, we present an accessible and cost-effective approach to building an exposure chamber in the lab.
Abdo Durra   +11 more
doaj   +1 more source

Swimming and the human microbiome at the intersection of sports, clinical, and environmental sciences: A scoping review of the literature. [PDF]

open access: yesFront Microbiol, 2022
Puce L   +11 more
europepmc   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Protocol to sequence markers from pollen grains carried by long-range migratory butterflies using metabarcoding

open access: yesSTAR Protocols
Summary: Molecular identification of pollen carried by insects informs about their history of visited plants. For migratory butterflies, it can be used to trace long-range movements enduring days of flight over thousands of kilometers. Here, we present a
Johanna Luise Gorki   +2 more
doaj   +1 more source

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