Results 71 to 80 of about 5,452,121 (296)

Outside, Looking In: Alternative Legacies and Futures for Surveillance Studies

open access: yes, 2022
In this dialogue, gender and women’s studies professors Toby Beauchamp (UIUC) and Ronak K. Kapadia (UIC) reflect on their early encounters with surveillance studies and the field’s shifting relationship to transnational feminist and queer of color ...
Kapadia, Ronak K., Beauchamp, Toby
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Molecular detection of a Leptospira lineage with high similarity to Leptospira kirschneri in human, environmental, and rodent samples from Gilan Province, Iran: an integrated field and laboratory investigation

open access: yesGMS Hygiene and Infection Control
Background: Leptospirosis remains an undercharacterized public health threat in Iran's Caspian coastal regions, despite high exposure risks within agricultural communities. Therefore, the circulation of Leptospira (L.) spp.
Mohammad Moradi Bazghaleh   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 43 2003 [PDF]

open access: yes, 2003
GP consultations rates for influenza-like illness increased during week 43 in Ireland. Influenza activity levels are higher than previously recorded for this time of year (the influenza surveillance scheme began in October 2000).
National Disease Surveillance Centre (NDSC)   +2 more
core  

Application of Artificial Intelligence in River Pollution Monitoring for Environmental Management Support and Impact Mitigation

open access: yesInfrastructures
Visible solid waste pollution in water bodies has intensified, threatening ecosystems and public health. This study proposes a low-complexity approach based on Convolutional Neural Networks (CNNs) for the automatic detection of visible litter in rivers ...
Jullia Fernandes Felizardo   +1 more
doaj   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu   +4 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 40 2003

open access: yes, 2003
Welcome to the first influenza surveillance report of the 2003/2004-influenza season. This is the fourth year of influenza surveillance using computerised sentinel general practices in Ireland.
National Disease Surveillance Centre (NDSC)   +2 more
core  

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