Results 51 to 60 of about 1,485,059 (284)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A scoping review of how the seven principles for building social-ecological resilience have been operationalized

Ecology and Society
Just over ten years ago, resilience scholars proposed seven principles for enhancing the resilience of social-ecological systems. The authors argued that there was a pressing need for a better understanding of how the principles can be operationalized ...
Julia Baird, Jessica L Blythe, Cal Murgu, Ryan Plummer   +3 more
doaj   +1 more source

Integration of environmental data in BIM tool & linked building data [PDF]

, 2019
Environmental assessment is a critical need to ensure building sustainability. In order to enhance the sustainability of building, involved actors should be able to access and share not only information about the building but also data about products and
Fonbeyin, Henry Abanda, Kamsu-Foguem, Bernard, Karray, Mohamed Hedi, Magniont, Camille, Pauwels, Pieter, Tchouangouem, Justine Floré   +5 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Enhancing nature-based tourism to improve wildlife conservation in Southern Africa: a synthetic review

Discover Sustainability
Wildlife is an essential resource for ecosystem balance, yet natural and anthropogenic forces in Southern Africa threaten its conservation. Due to wildlife over-exploitation, fauna conservation is at an embryonic stage in Southern Africa, and achieving ...
Elvis Batsirai Gumbo, Mark Makomborero Matsa, Pedzisai Kowe, Takunda Shabani, Tapiwa Shabani   +4 more
doaj   +1 more source

Building the future: integrating building information management and environmental assessment methodologies [PDF]

, 2012
The demand for sustainable buildings is increasing driven in part by legislation, rising energy costs and growing environmental concerns amongst consumers.
Alwan, Zaid, Hope, Alex
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Understanding occupational health challenges in managing hospital solid waste in Zimbabwe: a critical review

Discover Public Health
Industrialisation and service provision expose involved people to occupational health risks, including solid waste workers. In Zimbabwe, many concerns focus on occupational health risks affecting workers in industries, giving little attention to those ...
Steven Jerie, Timothy Vurayayi Mutekwa, Tapiwa Shabani, Takunda Shabani, Amato Chireshe   +4 more
doaj   +1 more source

Understanding environmental performance variation in manufacturing companies [PDF]

, 2013
Sustainability is an area of increasing interest for industry and its stakeholders, and some companies now aspire to address sustainability issues (e.g. carbon emissions) at strategic and operational levels.
Bocken, Nancy, Evans, Steve, Morgan, David   +2 more
core   +2 more sources