Results 141 to 150 of about 681,027 (341)

THE ENZYMATIC ACTIVATION OF SULFATE [PDF]

Proceedings of the National Academy of Sciences, 1955
H, Hilz, F, Lipmann
openaire   +2 more sources

Site-Directed Mutations at Phosphorylation Sites in Zea mays PHO1 Reveal Modulation of Enzymatic Activity by Phosphorylation at S566 in the L80 Region [PDF]

, 2023
Noman Shoaib, Nishbah Mughal, Lun Liu, Ali Raza, Leiyang Shen, Guowu Yu   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Lippia sidoides Cham. Compounds Induce Biochemical Defense Mechanisms Against Curvularia lunata sp. in Maize Plants

J
Corn (Zea mays L.) productivity is often compromised by phytosanitary challenges, with fungal disease like Curvularia leaf spot being particularly significant.
Bruna Leticia Dias, Talita Pereira de Souza Ferreira, Mateus Sunti Dalcin, Dalmarcia de Souza Carlos Mourão, Paulo Ricardo de Sena Fernandes, Taila Renata Neitzke, João Victor de Almeida Oliveira, Tiago Dias, Luis Oswaldo Viteri Jumbo, Eugênio Eduardo de Oliveira, Gil Rodrigues dos Santos   +10 more
doaj   +1 more source

The Effect of Respiration, pH, and Citrate Co-Metabolism on the Growth, Metabolite Production and Enzymatic Activities of Leuconostoc mesenteroides subsp. cremoris E30 [PDF]

, 2022
Annamaria Ricciardi, Livia Vanessa Storti, Marilisa Giavalisco, Eugenio Parente, Teresa Zotta   +4 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Crystallin‐gazing: unveiling enzymatic activity [PDF]

Journal of Neurochemistry, 2011
Patrick W, Reed, Robert J, Bloch
openaire   +2 more sources

In Vitro Cyclooxygenase-2 Protein Expression and Enzymatic Activity in Neoplastic Cells [PDF]

, 2007
David Heller, Timothy M. Fan, Louis‐Philippe de Lorimier, Sarah C. Charney, Anne M. Barger, Sarah H. Tannehill‐Gregg, Thomas J. Rosol, Matthew A. Wallig   +7 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Residual enzymatic activity as a prognostic factor in patients with Gaucher disease type 1: correlation with Zimran and GAUSS-I index and the severity of bone disease [PDF]

, 2016
Miguel Ángel Torralba, Susana Olivera, Juan Carlos Bureo, J. Dalmau, Ramiro Núñez, P. León, Jesús Villarrubia   +6 more
openalex   +1 more source