Results 101 to 110 of about 1,215,941 (358)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The activity of saccharolytic enzymes in Collembola is associated with species affinity for caves

International Journal of Speleology, 2018
The activity of enzymes associated with digestion can reflect food availability and feeding preferences of invertebrates in a particular habitat. Caves are mostly nutrient-poor habitats lacking primary production.
Andrea Parimuchová, Vladimír Šustr, Miloslav Devetter, Ondřej Vošta, Ionuţ Popa, Ľubomír Kováč   +5 more
doaj   +1 more source

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

The Influence of Sewage Sludge Composts on the Enzymatic Activity of Reclaimed Post-Mining Soil [PDF]

, 2023
Magdalena Myszura-Dymek, Grażyna Żukowska   +1 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Isolation of Native Fungi from Sawdust Collected at a Sawmill from Adeleke Area, Ogbomosho, Oyo State, Nigeria

Journal of Applied Sciences and Environmental Management
Sawdust is an agricultural waste and could be utilized in several productive and beneficial entities. Therefore, the objective of this paper is to assess the Isolation of Native Fungi from Sawdust collected at sawmill from Adeleke area, Ogbomosho, Oyo ...
A. P. Akomolafe, K. A. Odelade, S. O. Sulaimon   +2 more
doaj  

Prospection and Evaluation of (Hemi) Cellulolytic Enzymes Using Untreated and Pretreated Biomasses in Two Argentinean Native Termites [PDF]

, 2015
Saccharum officinarum bagasse (common name: sugarcane bagasse) and Pennisetum purpureum (also known as Napier grass) are among the most promising feedstocks for bioethanol production in Argentina and Brazil.
Arneodo Larochette, Joel Demián, Ben Guerrero, Emiliano, Bombarda Campanha, Raquel, Campos, Eleonora, Cataldi, Thaís Regiani, Cataldi, Ángel Adrián, Labate, Carlos A., Labate, Mônica T. Veneziano, Oliveira, Patrícia Abrão de, Rodrigues, Clenilson Martins, Talia, Paola Monica   +10 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of mash enzyme and heat treatments on the cellular antioxidant activity of black currant (Ribes nigrum), raspberry (Rubus idaeus), and blueberry (Vaccinium myrtillus) juices

CyTA - Journal of Food, 2017
The aim of this study was to determine the effect of mash enzymatic maceration and heating treatments before pressing on the antioxidant activities in selected berry juices.
Cecilia Bender, Karina V. Killermann, Dirk Rehmann, Helmut H. Weidlich   +3 more
doaj   +1 more source

Total Antioxidant Activity in Normal Pregnancy [PDF]

, 2009
Objective: Pregnancy is a state, which is more prone for oxidative stress. Various studies report development of a strong defence mechanisms against free radical damage, as the pregnancy progresses. Aim of our study is to assess the antioxidant status by
Adiga, MNS, Adiga, US
core   +1 more source