Results 111 to 120 of about 11,934 (247)

Metabolome and transcriptome integration explored the mechanism of browning in Glycyrrhiza uralensis Fisch cells

open access: yesFrontiers in Plant Science
IntroductionGlycyrrhiza uralensis Fisch, a traditional Chinese medicinal herb known for its diverse pharmacological effects including heat-clearing, detoxification, phlegm dissolving, and cough relief, has experienced an exponential increase in demand ...
Xinyang Zhao   +5 more
doaj   +1 more source

Bioinspired Interfacial Hydration Engineering via Metal–Organic Frameworks for Efficient Nitrate‐To‐Ammonia Conversion in Neutral Media

open access: yesAdvanced Science, EarlyView.
Inspired by Nitrite reductase, a metal–organic framework overlayer is introduced to regulate the interfacial hydration microenvironment on Cu electrodes, enriching hydrated K+ species that act as efficient proton donors. This strategy enables nitrate‐to‐ammonia conversion with near‐unity selectivity at industrial‐level current densities in neutral ...
Yuyin Mao   +4 more
wiley   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

A Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice

open access: yesAdvanced Science, EarlyView.
ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu   +13 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan   +11 more
wiley   +1 more source

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