Results 161 to 170 of about 9,008 (248)

A Historical Review of Enzymatic Debridement: Revisited

open access: yes, 2019
The following is an update to a book entitled, “A Historical Review of Enzymatic Debridement: Revisited”, which I wrote in 2003. Since its publication, while the relevant clinical evidence has remained consistent, the amount of biochemical research and knowledge gained has been impressive.
openaire   +1 more source

Rethinking Chronic Wound Treatment: Unlocking the Potential of Combination Products for an Unmet Multifactorial Need: A Review Study

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Chronic wounds, including diabetic foot, venous, and pressure ulcers, remain a major unmet medical challenge due to their prevalence, severity, and the limited efficacy of current treatments. These wounds are inherently multifactorial, requiring simultaneous intervention across all chronicity‐inducing factors.
Alberto Nicolás Ramos   +2 more
wiley   +1 more source

Evaluating the Effect of Therapeutic Antibiotics in Prosthetic Joint Infections Culturing: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims One of the important complications of knee and hip replacement arthroplasty is prosthetic joint infection (PJI), which is usually accompanied by negative culture that leads to severe consequences compared to positive ones. This study aims to evaluate the arbitrary use or mistreatment of antibiotics for therapeutic purposes ...
Moein Zangiabadian   +4 more
wiley   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon   +9 more
wiley   +1 more source

Lignin Nanoparticles Containing Cobalt‐Cyanine Complexes: Potential Multifunctional Platforms for Photoacoustic Imaging and Photothermal Treatment of Bacterial Biofilms in Chronic Wounds

open access: yesMacromolecular Bioscience, Volume 26, Issue 2, February 2026.
CoPc is combined with a lignin‐based material to obtain NPs sensitive to NIR irradiation and capable of ROS scavenging. Through the NPs, mild photothermal therapy can be achieved to act against bacterial biofilms. ABSTRACT Chronic wounds (CWs) are characterized by persistent inflammation and bacterial biofilms, which hinder healing and contribute to ...
Giulia Crivello   +13 more
wiley   +1 more source

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