Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
The Potential Role for a Painless Enzymatic Debridement Gel in Wound Bed Preparation for Venous Leg Ulcers-A Dose Escalation Study. [PDF]
Goldsmith D, Fairlamb DM.
europepmc +1 more source
(a) Schematic representation of the chemical cross‐linking of PVB/PCL‐TiO2‐RegIIIγ electrospun nanofibers. (b) Schematic illustration of the biomimetic dressing promoting healing in an exposed bone wound. The treatment of wounds with exposed bone has always been a difficult problem in the clinical treatment of orthopedics.
Chenhao Gong +6 more
wiley +1 more source
Role, Development, and Value of Enzymatic Debridement as Integral Component in Initial Treatment of Burn Injuries Exemplified by NexoBrid®. [PDF]
Mattern MM, Fuchs PC, Schiefer JL.
europepmc +1 more source
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo +10 more
wiley +1 more source
Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF). [PDF]
Waldner M +8 more
europepmc +1 more source
ABSTRACT Necrotising fasciitis (NF) is a rapidly progressing, life‐threatening infection with mortality rates that are exceedingly high. Despite the notably high risks of developing NF in patients with diabetes mellitus (DM), factors associated with mortality in this population are poorly understood.
Ashmit Daiyan Mustafa +6 more
wiley +1 more source
Exhaled Carbon Monoxide Indicates Persistent Subgingival Dysbiosis After Periodontal Therapy
ABSTRACT Aim To investigate whether exhaled carbon monoxide (CO) is dose‐dependently associated with subgingival polymicrobial clusters before and after non‐surgical periodontal therapy. Material and Methods We followed 163 adults with periodontitis, measuring CO before and at 2, 14 and 26 months after therapy.
Sophie Koehlen +14 more
wiley +1 more source
Evaluation of Papain-Urea for Enzymatic Debridement of Coagulation Zones Following Ablative Fractional Laser Treatment. [PDF]
Glahn JZ +7 more
europepmc +1 more source
Enzymatic Debridement for Burn Wound Care: Interrater Reliability and Impact of Experience in Post-intervention Therapy Decision. [PDF]
Siegwart LC +8 more
europepmc +1 more source

