Results 71 to 80 of about 4,916 (237)

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini   +11 more
wiley   +1 more source

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio   +4 more
wiley   +1 more source

Oxidized Bacterial Cellulose Membranes Immobilized with Papain for Dressing Applications: Physicochemical and In Vitro Biological Properties

open access: yesPharmaceutics
This research consolidates our group’s advances in developing a therapeutic dressing with innovative enzymatic debridement, focusing on the physicochemical and in vitro biological properties of papain immobilized in wet oxidized bacterial cellulose (OxBC–
Niédja Fittipaldi Vasconcelos   +6 more
doaj   +1 more source

Artisanal negative pressure therapy as an adjuvant to autograft skin in orthopedic trauma

open access: yesRevista de Enfermagem da Universidade Federal de Santa Maria, 2015
Aim: to describe the experience with the execution of artisanal negative pressure therapy as an adjunct to skin autograft in orthopedic trauma. Method: report based on practical experience on clinical management of complex wound in patients with an ...
Reginaldo Passoni   +5 more
doaj   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei   +9 more
wiley   +1 more source

Evaluation of burned hand function after enzymatic debridement.

open access: yes, 2021
20.500.12530/87857Hand burns are common injuries that can result in long-term impairment of hand function. Enzymatic debridement (ED) prevents damage to the viable dermis due to the procedure's selectivity and has become an option for obtaining an ...
González-Miranda, Álvaro   +3 more
core   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

open access: yesResponsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun   +8 more
wiley   +1 more source

EXPLORING THE EFFECTIVENESS OF ENZYMAT-IC DEBRIDEMENT IN DIABETIC FOOT ULCER HEALING:A SYSTEMATIC REVIEW

open access: yes, 2022
Introduction: Debridement is a critical procedure that can accelerate wound healing. One technique used in clinical practice to achieve debridement is enzymatic debridement, which is effective for all types of wounds.. Aim: This systematic review aims to
Polikandrioti,Maria   +3 more
core   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Comparative Outcomes of Endoscopic, Minimally Invasive Surgical, and Open Necrosectomy in Necrotizing Pancreatitis: Evidence From a Network Meta‐Analysis

open access: yesWorld Journal of Surgery, EarlyView.
The optimal interventional approach for necrotizing pancreatitis remains debated. We performed a systematic review with network meta‐analysis and proportional meta‐analysis to compare endoscopic trans‐gastric necrosectomy (EN), minimally invasive surgical necrosectomy (MIN), and open necrosectomy (ON).
Ahmed Abdelsamad   +10 more
wiley   +1 more source

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