Results 71 to 80 of about 352,969 (309)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Effect of Different Proteases on the Enzymatic Hydrolysis Efficiency and Structure of Wheat Gluten

Shipin gongye ke-ji
This study aimed to investigate the enzymatic hydrolysis effects of papain, alkaline protease, neutral protease, alkaline protease TG enzyme combination, and papain alkaline protease combination on gluten protein and their impact on its structure.
Xiangjun LIU, Yuting ZHANG, Xuedong WANG, Yan WU, Ku LI, Huai XU   +5 more
doaj   +1 more source

Enzymatic Hydrolysis of Acyl Naphthylamines.

Experimental Biology and Medicine, 1954
ConclusionsAn enzyme, hydrolyzing acyl naphthylamines, can be demonstrated in a number of tissues and in serum. Chloroacetyl naphthylamines are hydrolyzed at a much higher rate than the corresponding acetyl compounds. It is possible to localize the enzyme histochemically in some tissues.
openaire   +2 more sources

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

Advanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin, Anila Antony, Hongtao Cai, Antonia Debevc, Ceyda Topal, Anne Linhardt, Alla Synytska, Leonid Ionov   +7 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Modeling of lactose enzymatic hydrolysis using Monte Carlo method

Electronic Journal of Biotechnology, 2019
Background: Mathematical modeling is useful in the analysis, prediction, and optimization of an enzymatic process. Unlike the conventional modeling methods, Monte Carlo method has special advantages in providing representations of the molecule’s spatial ...
Ling Gao, Qingqing Guo, Huibin Lin, Deng Pan, Xiaodong Huang, Jianqun Lin, Jianqiang Lin   +6 more
doaj   +1 more source

Research of influence of technological processing parameters of protein-fat base for supply of sportsmen on activity of protease inhibitors [PDF]

, 2017
The object of research is the biological value of the protein-fat base for athletes, workers of heavy physical labor, military personnel, depending on the conditions of its preliminary processing.
Belinska, Anna, Bochkarev, Sergiy, Krichkovska, Lidiya, Petrov, Serhii, Petrova, Iryna, Varankina, Oleksandra   +5 more
core   +1 more source

Optimization of cellobiohydrolase production and secretome analysis of Trametes villosa LBM 033 suitable for lignocellulosic bioconversion [PDF]

, 2019
The production of bioethanol from lignocellulosic biomass comprises the enzymatic hydrolysis of lignocellulosic structures by three major cellulases. Among them, cellobiohydrolases are considered to be key enzymes playing a significant role on cellulose ...
Burgos Fonseca, María Isabel, Campos, Eleonora, Coniglio, Romina Olga, Díaz, Gabriela Verónica, Ghio, Silvina, Ontañon, Ornella Mailén, Zapata, Pedro Dario   +6 more
core   +2 more sources

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Production of bioethanol from multiple waste streams of rice milling [PDF]

, 2017
This work describes the feasibility of using rice milling by-products as feedstock for bioethanol. Starch-rich residues (rice bran, broken, unripe and discolored rice) were individually fermented (20% w/v) through Consolidated Bioprocessing by two ...
Basaglia, Marina, Cagnin, Lorenzo, Casella, Sergio, Favaro, Lorenzo, Pizzocchero, Valentino, van Zyl, Willem Heber   +5 more
core   +1 more source