Results 41 to 50 of about 6,595,197 (312)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Enzymatic properties of the neuraminidase of recombinant H1N1 influenza viruses.

, 2018
Enzymatic properties of the neuraminidase of recombinant H1N1 influenza viruses.
Natalia A. Ilyushina (44418), Vladimir Y. Lugovtsev (458546), Alexey M. Khalenkov (5076794), Anastasia P. Samsonova (4281937), Nicolette Lee (5076791), Derek D. Ireland (5076788), Nicolai V. Bovin (44421), Raymond P. Donnelly (317850)   +7 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A novel recombinant oligogalacturonide lyase from Klebsiella variicola promotes pectin degradation and enhances aroma formation in tobacco leaves

Frontiers in Bioengineering and Biotechnology
Microbial enzymes can be exploited to improve the sensory quality and reduce the harmful effects of tobacco-originated compounds in tobacco-derived products.
Shen Huang, Caiping Chang, Aamir Rasool, Robina Manzoor, Chao Liu, Ruoxin Wu, Jialiang Wang, Duobin Mao   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect of Enzyme Type on the Antioxidant Activities and Functional Properties of Enzymatic Hydrolysates from Sea Cucumber (Cucumaria frondosa) Viscera

, 2016
Effects of various proteases were obvious on the amino acid composition, antioxidant activities, and functional properties of enzymatic hydrolysates prepared from sea cucumber viscera (SCV). Alcalase, trypsin, and flavourzyme conferred better antioxidant
Tao, HT, Yan, MY, Qin, S, Qin, S (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, 17 Chunhui Rd, Yantai 264003, Shandong, Peoples R China. Email:mingyan012003@163.com   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Keratinases: microbial sources, mechanisms, and industrial applications in waste valorization

Frontiers in Microbiology
Keratinous waste, a major by-product of agriculture and animal husbandry, is produced in massive quantities and is notoriously recalcitrant to degradation.
Yuqing Chu, Shan Chu, Fengna Hu, Mohan Huang, Haoran Lu, Zhiqiao Liu, Fenglian Shan, Xiaotang Chen   +7 more
doaj   +1 more source

Pseudo-Enzymatic Properties of Haptoglobin:Hemoglobin Complexes [PDF]

American Journal of Biomedical Science & Research, 2019
n ...
openaire   +2 more sources

Programming properties of transient hydrogels by an enzymatic reaction [PDF]

Nanoscale, 2020
Here we created a dynamic gel system that allows programming of a metastable assembly state which eventually drives the system to a new material exhibiting a gel-to-gel transition.
Santanu Panja, Kamila Boháčová, Bart Dietrich, Dave J. Adams   +3 more
openaire   +3 more sources