In vivo activation of methyl-coenzyme M reductase by carbon monoxide
Frontiers in Microbiology, 2013 Methyl-coenzyme M reductase (MCR) from methanogenic archaea catalyzes the rate-limiting and final step in methane biosynthesis. Using coenzyme B (CoBSH) as the two-electron donor, MCR reduces methyl-coenzyme M (CH3-SCoM) to methane and the mixed ...
Yuzhen eZhou +2 more
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Cold-Water Immersion Promotes Antioxidant Enzyme Activation in Elite Taekwondo Athletes
Applied Sciences, 2021 The aim of this study was to investigate the effect of cold-water immersion (CWI) on lipid peroxides and antioxidant enzymes in adult Taekwondo athletes after a match. A cross-sectional study was performed.
Eun-Hee Park +2 more
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Enzymatic functionalization of carbon-hydrogen bonds [PDF]
, 2011 The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H. +2 more
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Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia
Química Nova, 2006 Strategies that promote selective activation of prodrugs by enzymes can be divided into two major classes: 1) deliver of a monoclonal antibody-enzyme immunoconjugate that can recognize a specific antigen and promote the prodrug to a citotoxic drug, with ...
Lorena Blau +2 more
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Unraveling the activation mechanism of the potato tuber ADP-glucose pyrophosphorylase. [PDF]
PLoS ONE, 2013 ADP-glucose pyrophosphorylase regulates the synthesis of glycogen in bacteria and of starch in plants. The enzyme from plants is mainly activated by 3-phosphoglycerate and is a heterotetramer comprising two small and two large subunits.
Carlos M Figueroa +6 more
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Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19
Journal of Innate Immunity, 2022 Mannose-binding lectin-associated serine protease 2 (MASP-2) is the main activator of the lectin complement pathway and has been suggested to be involved in the pathophysiology of coronavirus disease 2019 (COVID-19).
Maximilian Peter Götz +8 more
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Deactivation of TEM-1 beta-Lactamase investigated by isothermal batch and non-isothermal continuous enzyme membrane reactor methods [PDF]
, 2009 The thermal deactivation of TEM-1 β-lactamase was examined using two experimental techniques: a series of isothermal batch assays and a single, continuous, non-isothermal assay in an enzyme membrane reactor (EMR).
Bommarius, Andreas S. +2 more
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Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]
, 2007 MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia +6 more
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An Extended Polyanion Activation Surface in Insulin Degrading Enzyme.
PLoS ONE, 2015 Insulin degrading enzyme (IDE) is believed to be the major enzyme that metabolizes insulin and has been implicated in the degradation of a number of other bioactive peptides, including amyloid beta peptide (Aβ), glucagon, amylin, and atrial natriuretic ...
Eun Suk Song +9 more
doaj +1 more source
Transient signal generation in a self-assembled nanosystem fueled by ATP [PDF]
, 2015 A fundamental difference exists in the way signal generation is dealt with in natural and synthetic systems. While nature uses the transient activation of signalling pathways to regulate all cellular functions, chemists rely on sensory devices that ...
Pezzato, Cristian, Prins, LEONARD JAN
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