Results 61 to 70 of about 1,788,718 (217)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The effects of trace elements, cations, and environmental conditions on protocatechuate 3,4-dioxygenase activity

Scientia Agricola, 2013
Phenanthracene is a highly toxic organic compound capable of contaminating water and soils, and biodegradation is an important tool for remediating polluted environments.
Andréa Scaramal da Silva, Rodrigo Josemar Seminoti Jacques, Robson Andreazza, Fátima Menezes Bento, Flávio Anastácio de Oliveira Camargo   +4 more
doaj  

Biochemical characterization of pectinase activity from the digestive midgut fluid of larvae and adult of the Colorado potato beetle, Leptinotarsa decemlineata (Col: Chrysomelidae) [PDF]

Arthropods, 2015
The study of pectinase enzyme in potato leaf beetle that is the most important pest of potatoes consider as an effective way to develop control methods because this enzyme is important in degrading plant cell wall.
Razieh Karimi, Majid Kazzazi, Mohammad Vatanparast   +2 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Study on the Differentiation Characteristics of Different Sandy Vegetation Soil Enzyme Activities

Shuitu baochi yanjiu, 2010
Taking the nine kinds of sandy vegetation planted in Psammophyte garden,Yulin city of Shaanxi province as the research object,and also selecting the bare sand as the control.In the paper,differentiation characteristics of nutrient and enzyme activities ...
YU Na1, LIU Ji-ming1, ZHANG Chao2, DAI Quan-hou1   +3 more
doaj  

Antibacterial Activity of Bacteriophage Lytic Enzyme Ply900

Veterinary Sciences
S. suis is a prominent zoonotic pathogen responsible for diseases such as arthritis in piglets, swine septicemia, and meningitis. The emergence of multi-drug resistance (MDR) underscores the urgent need for the development of novel antibacterial ...
Yuan Li, Luxiang Xu, Yuhan Zhang, Chunliu Dong, Han Zhou   +4 more
doaj   +1 more source

Aspects of protease from isolated bacteria from bovine milk [PDF]

Archives of Agriculture Sciences Journal
Ninety-five isolates were screened for produce of protease enzymes. The most potent isolate was identified as Bacillus sp. The aim of study is production and characterization of protease from selected isolate.
Sahar Mahmoud, S. Ali, Kh. Salman
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source