Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source
A novel strategy for ultrasound-assisted immobilized enzyme hydrolysis for the preparation of yak bone collagen peptides: Process optimization, structure and antioxidant mechanisms. [PDF]
Ultrason SonochemCao Y, Song Z, Ma Y, Luo Y, Qi J.
europepmc +1 more source
Advanced Science, EarlyView.By exploiting multiscale hydrogen‐bonding interactions between HFPD and TOCNF, the composite simultaneously achieves a high piezoelectric coefficient (14.0 pC·N−1), outstanding flexibility (100 000 bending cycles), water‐assisted recyclability, excellent biodegradability, and sensitive wearable/implantable sensing for motion, speech, and Morse code ...
Tingshuai Luo +9 more
wiley +1 more source
Pulsed Electric Field Pretreatment Enhances the Enzyme Hydrolysis of Baker's Yeast. [PDF]
MicroorganismsVeleva R, Ganeva V, Zhiponova M.
europepmc +1 more source
The enzymic hydrolysis and structure of phosphatidyl glycerol [PDF]
Biochimica et Biophysica Acta, 1962 Haverkate, F. +2 more
openaire +3 more sources
Advanced Science, EarlyView.A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li +4 more
wiley +1 more source
Yeast enzyme hydrolysis slurry supplementation improves growth, intestinal health, and metabolic responses in juvenile largemouth bass (Micropterus salmoides) fed soybean meal-based diets with partial fishmeal replacement. [PDF]
J Anim Sci BiotechnolWen J +12 more
europepmc +1 more source
Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution
Advanced Science, EarlyView.MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge +6 more
wiley +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Controlling enzyme hydrolysis of branched polymers synthesised using transfer-dominated branching radical telomerisation via telogen and taxogen selection. [PDF]
Commun ChemMckeating S +9 more
europepmc +1 more source