Results 251 to 260 of about 285,607 (309)

Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery

Angewandte Chemie, EarlyView.
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne, Sona Krajcovicova, Graeme Davies, Hannah Bolt, Jefferson Revell, David R. Spring   +5 more
wiley   +1 more source

Innovative discovery and validation of ACE-inhibitory peptides from eggshell membrane keratin byproducts: An integrated computational and <i>in vitro</i> approach. [PDF]

Curr Res Food Sci
Xu T, Yang J, Gong L, Li H, Zhao K, Wang Z, Tang H.   +6 more
europepmc   +1 more source

Electroenzymatic CO2 Fixation

Angewandte Chemie International Edition, EarlyView.
Electroenzymatic CO2 fixation enables energy‐efficient, highly selective synthesis of complex molecules. Unlocking its full potential requires fundamental understanding of electrode‐coupled reductases and carboxylases. This review critically discusses available enzymes, product scope, and key thermodynamic and kinetic considerations, highlighting ...
Leonardo Castañeda‐Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré   +4 more
wiley   +1 more source

Bioactive Peptides from <i>Astrocaryum murumuru</i> Residual Biomass: Enzymatic Hydrolysis, Characterization, and Functional Activities. [PDF]

Foods
Pantoja GV, Serrão JMS, Moraes VSV, Lima JAF, Beraldo-Neto E, Oliveira JAR, Martins LHDS, Pimenta DC, Fontanari GG.   +8 more
europepmc   +1 more source

High-Value Transformation of Rice-Derived Bioactive Peptides for Multiscenario Applications: From AI-Aided Design to Molecular Modification. [PDF]

Int J Food Sci
Yao T, Yao J, Zhang Q, Huang M, Han Y, Li Q, Zhang M, Li L.   +7 more
europepmc   +1 more source

The Next Frontier in Biodegradable Plastics: Enzyme-Embedding Biodegradable Polymers. [PDF]

Biomacromolecules
Huang Q, Kimura S, Iwata T.
europepmc   +1 more source

Recent advances in biomass deconstruction, microbial conversion, artificial intelligence, and carbon capture for sustainable bioenergy. [PDF]

Bioresour Bioprocess
Kumar V, Mishra S, Joshi P, Misra J, Yegneswaran PP, Mallikarjun B, Yazdani SS, Lal PB.   +7 more
europepmc   +1 more source

Thermolysin Versus Four Commercial Proteases in the Modification of Soy Protein Isolate: Structural, Functional, and Taste Characterization. [PDF]

Foods
Liu X, Yin J, Yin S, Chen P, Zhang B.
europepmc   +1 more source

In Silico and In Vitro Screening and Mechanisms of Angiotensin I-Converting Enzyme Inhibitory Peptides from Protein Hydrolysates of Royal Jelly. [PDF]

Foods
Zhang Y, Guo S, Miao H, Gu Y, Zhang J.
europepmc   +1 more source

Safety evaluation of an extension of use of the food enzyme glucan 1,4-α-maltohydrolase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-CY. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Baviera JMB, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Bonino I, Cavanna D, Liu Y.   +15 more
europepmc   +1 more source