Results 1 to 10 of about 3,652 (96)
Induction and Characterisation of Lignocellulolytic Activities from Novel Deep-Sea Fungal Secretomes
Fungi are increasingly recognised as being able to inhabit extreme environments. The deep sea is considered an extreme environment because of its low temperatures, high hydrostatic and lithostatic pressures, 3.5% salinity, and low oxygen, nutrient and ...
Bronwyn Dowd, Maria G. Tuohy
doaj +1 more source
Dabrafenib inhibits the cell proliferation of metastatic melanoma with the oncogenic BRAF(V600)-mutation. However, dabrafenib monotherapy is associated with pERK reactivation, drug resistance, and consequential relapse. A clinical drug-dose determination
Marco Albrecht +3 more
doaj +1 more source
Azole fungicides, especially triazole compounds, are widely used in agriculture and as pharmaceuticals. For a considerable number of agricultural azole fungicides, the liver has been identified as the main target organ of toxicity.
Philip Marx-Stoelting +2 more
doaj +1 more source
Studies on new microbial sources of cellulase and accurate assessment of the steps that increase cellulase production are essential strategies to reduce costs of various processes using such enzymes.
Genilton da Silva Faheina Junior +5 more
doaj +1 more source
Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data. [PDF]
Induction of cytochrome P450 3A4 (CYP3A4) expression is often implicated in clinically relevant drug-drug interactions (DDI), as metabolism catalyzed by this enzyme is the dominant route of elimination for many drugs.
Fumiyoshi Yamashita +7 more
doaj +1 more source
Controversies in contraception for women with epilepsy
Contraception is an important choice that offers autonomy to women with regard to prevention of unintended pregnancies. There is wide variation in the contraceptive practices between continents, countries, and societies.
Sanjeev V Thomas
doaj +1 more source
Aflatoxin B1 Conversion by Black Soldier Fly (Hermetia illucens) Larval Enzyme Extracts
The larvae of the black soldier fly (Hermetia illucens L., BSFL) have received increased industrial interest as a novel protein source for food and feed.
Nathan Meijer +5 more
doaj +1 more source
Improved expression of Catechol 1,2-dioxygenase gene from Burkholderia cepacia in Escherichia coli
Catechol 1,2-dioxygenase (CAT1) is a key enzyme for the ortho-cleavage pathway involved in the degradation of dibenzofuran, a dioxin derivative, which is a highly toxic environmental pollutant.
Van Thanh Dang +5 more
doaj +1 more source
Seven medicinal plants popularly used for treating malaria in West Africa were selected to assess herb-drug interaction potential through a series of in vitro methods.
Pius S. Fasinu +5 more
doaj +1 more source
Study on Ligninase Activity of Aspergillus fumigatus G13 Induced by Lignin Model Compounds
With the ligninase activity as an index, three model compounds, ferulic acid, pcoumaric acid and sinapic acid, were used as substrates to study the characteristics of Aspergillus fumigatus G13 induced enzyme production by adding cellulose and glucose and
FENG Qian, YAN Hong
doaj +1 more source

