Results 111 to 120 of about 966,113 (164)

Beyond IC50-A computational dynamic model of drug resistance in enzyme inhibition treatment. [PDF]

PLoS Comput Biol
Roadnight Sheehan J, de Wijn AS, Freire TS, Friedman R.   +3 more
europepmc   +1 more source

Bidirectional Enzyme Inhibition and Activation for In Situ Formation of Injectable Hydrogel Using a Bispecific Aptamer. [PDF]

Langmuir
Wen C, Lee K, Wang Y, Wang X, Wang Y.
europepmc   +1 more source

Comprehensive LC-ESI-HRMS/MS Profiling and Assessment of Texture, Predicted Glycaemic Index, Antioxidant Activity and Digestive Enzyme Inhibition of Gluten- and Lactose-Free Cookies Enriched with Pomegranate By-Products. [PDF]

Foods
Pino R, Tundis R, Sicari V, Mincione A, Gattuso A, La Torre C, Fazio A, Piacente S, Masullo M, Cerulli A, Loizzo MR.   +10 more
europepmc   +1 more source

Multivariate Evaluation of Biofunctional Metabolites in Korean Soybean Cultivars by Use Categories: Assessment of Antioxidant and Enzyme Inhibition Activities. [PDF]

Antioxidants (Basel)
Cho KM, Jeon SH, Ko EJ, Park DH, Jeong YR, Cho DY, Kim JH, Lee JH.   +7 more
europepmc   +1 more source

HPLC, GC-MS, XRD profiling, enzyme inhibition and cytotoxicity potential of Phlomis Stewartii extracts using response surface methodology. [PDF]

BMC Plant Biol
Rasheed MU, Rashid H, Iman S, Oranab S, Rahim MA, Mahmoud MH, Castro-Muñoz R, Zongo E.   +7 more
europepmc   +1 more source

Influence of silver nanoparticles on the in vitro growth, phenolic profile, antioxidant potential, enzyme inhibition, and essential oil composition of Clinopodium nepeta subsp. spruneri (Boiss.) Bartolucci & F. Conti. [PDF]

Sci Rep
Bektaş E.
europepmc   +1 more source

Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity. [PDF]

J Med Chem
Flury P, Vishwakarma J, Sylvester K, Higashi-Kuwata N, Dabrowska AK, Delgado R, Cuell A, Basu R, Taylor AB, de Oliveira EG, Magalhães Serafim MS, Qiao J, Chen Y, Yang S, O'Donoghue AJ, Mitsuya H, Gütschow M, Laufer SA, Müller CE, Harris RS, Pillaiyar T.   +20 more
europepmc   +1 more source

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Enzyme Inhibition

2023
This chapter discusses enzyme inhibition. A major aspect of the regulation of enzyme activity and therefore of the balance of reaction rates in organisms is the possibility that a compound can inhibit the enzyme's action. The modulation of the activity of enzymes with effector molecules is essential for the coordination of the huge number of reactions ...
Pranati Das, Bhuyan, Jyoti Krishna, Subhashree Kabi, Harapriya Moahanta, Pradhan, Rahul   +4 more
openaire   +2 more sources

Enzyme induction and inhibition

Pharmacology & Therapeutics, 1990
The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range
M, Barry, J, Feely
openaire   +2 more sources

Enzyme Inhibition

Current Bioactive Compounds, 2007
One aspect of the importance of enzymes in biology can be appreciated by considering the attention that continues to be focused on the inhibition of enzymatic activity. Historically, inhibitors played important roles in the elucidation of metabolic pathways.
Perry A. Frey, Adrian D. Hegeman
  +4 more sources