Results 201 to 210 of about 4,881,376 (355)

Enzyme Catalysis and Enzyme Inhibition [PDF]

, 2014
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration. [PDF]

Nat Commun
Jang HJ, Song YM, Jeon JS, Yun HY, Kim SK, Kim JK.   +5 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Phytoconstituents, antioxidant and enzyme inhibition activities of coffee beans through widely targeted metabolomes and <i>in vitro</i> arrays. [PDF]

Food Chem X
Wang Y, Huang Z, He H, Zhou X, Yang D, Shu P, Chen X, Cheng J, Ma Y.   +8 more
europepmc   +1 more source

Enzymes and Inhibitants [PDF]

Scientific American, 1912
openaire   +1 more source

Inhibition of dipeptidyl peptidase-IV enzyme activity protects against myocardial ischemia-reperfusion injury in rats [PDF]

, 2014
Sarah Chua, Fan-Yen Lee, Tzu‐Hsien Tsai, Jiunn‐Jye Sheu, Steve Leu, Cheuk‐Kwan Sun, Yung‐Lung Chen, Hsueh‐Wen Chang, Han‐Tan Chai, Chu-Feng Liu, Hung‐I Lu, Hon‐Kan Yip   +11 more
openalex   +1 more source

Serum-Mediated Inhibition of Enzyme Replacement Therapy in Fabry Disease.

Journal of the American Society of Nephrology, 2016
Malte Lenders, J. Stypmann, T. Duning, Boris Schmitz, S. Brand, E. Brand   +5 more
semanticscholar   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Comparative Evaluation of the Digestive Enzyme Inhibition, Protein, and Starch Components of Ten <i>Macrotyloma uniflorum</i> (Lam.) Verdc. Accessions. [PDF]

Plants (Basel)
Ogunniyi QA, Molokwu AF, Nkumah AO, Adegoke AA, Oyatomi OA, Ogbole OO, Odeku OA, Fettke J, Abberton MT.   +8 more
europepmc   +1 more source