Results 201 to 210 of about 1,038,872 (308)

Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition. [PDF]

Int J Mol Sci
Reynoso-García MF, Nicolás-Álvarez DE, Tenorio-Barajas AY, Reyes-Chaparro A.   +3 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Characterization of Bromelain-Soluble Sheepskin (Ovis aries) Proteins and Effect of In Vitro Gastrointestinal Digestion on Angiotensin Converting Enzyme Inhibition Activity. [PDF]

Food Sci Nutr
Putri DPT, Gallego M, Abidin MZ, Fitriyanto NA, Mora L, Toldrá F, Erwanto Y.   +6 more
europepmc   +1 more source

Inhibition of lysosomal enzymes by dapsone

British Journal of Dermatology, 1975
P D, Mier, J J, van den Hurk
openaire   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Integrative Pharmacological and Computational Analysis of <i>Abelmoschus esculentus</i> Phytochemicals: Enzyme Inhibition, Molecular Docking, and Dynamics Simulation Against Key Antidiabetic Targets. [PDF]

Life (Basel)
Banu H, Al-Shammari E, Bardakci F, Patel M, Adnan M, Khan MI, AlFahhad N, Ashraf SA.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Dose-Dependent Effects of Pear (<i>Pyrus communis</i> L.) Juice on Kombucha Polyphenols, Antioxidant Capacity, and Enzyme Inhibition. [PDF]

Molecules
Kuraj A, Kolniak-Ostek J.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Integrated In Vitro and In Silico Profiling of Piperazinyl Thiosemicarbazone Derivatives Against Trypanosoma cruzi: Stage-Specific Activity and Enzyme Inhibition. [PDF]

Pharmaceuticals (Basel)
Baldoni HA, Sbaraglini ML, Balcazar DE, Arias DG, Guerrero SA, Alba Soto CD, Cieslik W, Rogalska M, Polański J, Enriz RD, Jampilek J, Musiol R.   +11 more
europepmc   +1 more source