Antidiabetic Effects of Ethanolic Extract of <i>Macrothelypteris torresiana</i> : <i>In Vitro</i> Enzyme Inhibition and <i>In Vivo</i> Evaluation in Streptozotocin-Induced Sprague-Dawley Rats. [PDF]
Prabhath K +3 more
europepmc +1 more source
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko +4 more
wiley +1 more source
Dose-Dependent Effects of Pear (<i>Pyrus communis</i> L.) Juice on Kombucha Polyphenols, Antioxidant Capacity, and Enzyme Inhibition. [PDF]
Kuraj A, Kolniak-Ostek J.
europepmc +1 more source
Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo +6 more
wiley +1 more source
Integrative Pharmacological and Computational Analysis of <i>Abelmoschus esculentus</i> Phytochemicals: Enzyme Inhibition, Molecular Docking, and Dynamics Simulation Against Key Antidiabetic Targets. [PDF]
Banu H +7 more
europepmc +1 more source
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source
Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration. [PDF]
Jang HJ +5 more
europepmc +1 more source
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang +4 more
wiley +1 more source
Phytochemical analysis and enzyme inhibition of Origanum dictamnus L essential oil through in vitro and in silico methods. [PDF]
Amato G +6 more
europepmc +1 more source

