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2023
This chapter discusses enzyme inhibition. A major aspect of the regulation of enzyme activity and therefore of the balance of reaction rates in organisms is the possibility that a compound can inhibit the enzyme's action. The modulation of the activity of enzymes with effector molecules is essential for the coordination of the huge number of reactions ...
Pranati Das +4 more
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This chapter discusses enzyme inhibition. A major aspect of the regulation of enzyme activity and therefore of the balance of reaction rates in organisms is the possibility that a compound can inhibit the enzyme's action. The modulation of the activity of enzymes with effector molecules is essential for the coordination of the huge number of reactions ...
Pranati Das +4 more
openaire +2 more sources
ENZYME INHIBITION BY ANTIBODIES
Acta Endocrinologica, 1975ABSTRACT The interest in the inhibition of enzymes by their specific antibodies stems mainly from the fact that these systems can serve as suitable models in the study of neutralization of biologically active molecules in general. The interaction of enzymes with their specific antibodies generally leads to a reduction in their enzymatic ...
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Inhibition of enzymes by lipoproteins
Biochimica et Biophysica Acta, 1956Abstract 1. 1. Experiments designed to test the specificity of lipoproteins as inhibitors of glucose utilisation are presented. 2. 2. It has been shown that the difference between normal and diabetic plasma in regard to content of this material is largely quantitative. 3. 3.
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Food Chemistry, 2021
The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis +5 more
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The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis +5 more
semanticscholar +1 more source
Pesticide Detection in Vegetable Crops Using Enzyme Inhibition Methods: a Comprehensive Review
Food Analytical Methods, 2022Heba Bedair +6 more
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Diagnosis of enzyme inhibition based on the degree of inhibition
Biochimica et Biophysica Acta (BBA) - General Subjects, 2003In this work, a method for the diagnosis of kinetic inhibition, based on the dependence of the degree of inhibition (epsilon(i)) on the inhibitor concentration [I] and on the substrate concentration [S], is presented. Because the degree of inhibition is a ratio between rates, kinetic data are normalized by the introduction of an internal control-the ...
Antunes, Fernando +4 more
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Clinical Implications of Enzyme Induction and Enzyme Inhibition
Clinical Pharmacokinetics, 1981The pharmacological effect of a drug is partly dependent upon its concentration at its site of action, which in turn is partly dependent upon its rate of elimination. The rate of elimination of many lipophilic drugs is governed by the activity of the hepatic microsomal mixed-function oxidases.
B K, Park, A M, Breckenridge
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Angiotensin converting enzyme inhibition and renin inhibition
Journal of Hypertension, 1989Over a period of several years, methods of measuring circulating angiotensin II have been progressively improved and it has now become possible to measure circulating angiotensin II with a high degree of accuracy. The main ingredients in this new methodology are bonded-phase silica for quantitative angiotensin extraction from biological fluids and ...
Nussberger J, Waeber B, Brunner HR
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Enzyme inactivation and inhibition by Gossypol
Molecular and Cellular Biochemistry, 1982Three lactate dehydrogenase isozymes and malate dehydrogenase purified from mouse tissues were inactivated with time by low concentration of gossypol. The degree of enzyme inactivation is both gossypol- and enzyme-concentration-dependent. Under the same experimental conditions, lactate dehydrogenase-X and lactate dehydrogenase-5 were inactivated faster
C Y, Lee +3 more
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