Results 1 to 10 of about 700,344 (208)

Nanozymes as Enzyme Inhibitors

International Journal of Nanomedicine, 2021
Yaling Huang,1 Jian Jiang,1 Yanqiu Wang,1 Jie Chen,1 Juqun Xi1,2 1Institute of Translational Medicine, Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, 225001, People’s Republic of China; 2Jiangsu Key ...
Huang Y, Jiang J, Wang Y, Chen J, Xi J
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Enzymes and Enzyme Inhibitors-Applications in Medicine and Diagnosis. [PDF]

Int J Mol Sci, 2023
This is the first part of a Special Issue on enzymes and enzymes inhibitors and their applications in medicine and diagnosis [...]
Geronikaki A, Eleutheriou PT.
europepmc   +3 more sources

Enzyme Inhibitors as Multifaceted Tools in Medicine and Agriculture [PDF]

Molecules
Enzymes are molecules that play a crucial role in maintaining homeostasis and balance in all living organisms by catalyzing metabolic and cellular processes.
Sonia Del Prete, Mario Pagano
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Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors

Exploration of Targeted Anti-tumor Therapy, 2023
Aim: Human histone deacetylase 8 (KDAC8) is a well-recognized pharmaceutical target in Cornelia de Lange syndrome and different types of cancer, particularly childhood neuroblastoma.
Markus Schweipert, Anuja Amurthavasan, Franz-Josef Meyer-Almes   +2 more
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Mechanistic Aspects of Apiaceae Family Spices in Ameliorating Alzheimer’s Disease

Antioxidants, 2021
Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases worldwide. In an effort to search for new strategies for treating AD, natural products have become candidates of choice.
Niti Sharma, Mario A. Tan, Seong Soo A. An   +2 more
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Phytochemical Composition, Antioxidant, and Enzyme Inhibition Activities of Methanolic Extracts of Two Endemic Onosma Species

Plants, 2021
Onosma species have been used as a dye for hundreds of years due to their dark red pigments. These species have also been used by mankind in the treatment of various diseases since ancient times.
Kandasamy Saravanakumar, Cengiz Sarikurkcu, Saliha Seyma Sahinler, Rabia Busra Sarikurkcu, Myeong-Hyeon Wang   +4 more
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Enzyme Inhibitors from Gorgonians and Soft Corals

Marine Drugs, 2023
For decades, gorgonians and soft corals have been considered promising sources of bioactive compounds, attracting the interest of scientists from different fields. As the most abundant bioactive compounds within these organisms, terpenoids, steroids, and
Andrea Córdova-Isaza, Sofía Jiménez-Mármol, Yasel Guerra, Emir Salas-Sarduy   +3 more
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Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication

Viruses, 2023
Viral replication often depends on RNA maturation and degradation processes catalyzed by viral ribonucleases, which are therefore candidate targets for antiviral drugs.
Abhishek Asthana, Angela Corona, Woo-Jin Shin, Mi-Jeong Kwak, Christina Gaughan, Enzo Tramontano, Jae U. Jung, Rainer Schobert, Babal Kant Jha, Robert H. Silverman, Bernhard Biersack   +10 more
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Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families

Marine Drugs, 2023
Proteolytic enzymes, also known as peptidases, are critical in all living organisms. Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate many biochemical and physiological processes.
Isel Pascual Alonso, Fabiola Almeida García, Mario Ernesto Valdés Tresanco, Yarini Arrebola Sánchez, Daniel Ojeda del Sol, Belinda Sánchez Ramírez, Isabelle Florent, Marjorie Schmitt, Francesc Xavier Avilés   +8 more
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Phytochemicals and Enzyme Inhibitory Capacities of the Methanolic Extracts from the Italian Apple Cultivar Mela Rosa dei Monti Sibillini

Pharmaceuticals, 2020
The phytochemical profile of the methanolic extracts (pulp and peel) obtained from two dehydration methods (drying and freeze-lyophilization) of the traditional Italian apple Mela Rosa dei Monti Sibillini, as well as their inhibitory properties against ...
Víctor López, Francisco Les, Serena Mevi, Joice Guileine Nkuimi Wandjou, Guillermo Cásedas, Giovanni Caprioli, Filippo Maggi   +6 more
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