Results 1 to 10 of about 5,417,177 (410)
Nanozymes as Enzyme Inhibitors
International Journal of Nanomedicine, 2021 Yaling Huang,1 Jian Jiang,1 Yanqiu Wang,1 Jie Chen,1 Juqun Xi1,2 1Institute of Translational Medicine, Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, 225001, People’s Republic of China; 2Jiangsu Key ...
Huang Y, Jiang J, Wang Y, Chen J, Xi J
doaj +6 more sources
A folding inhibitor of the HIV-1 Protease [PDF]
arXiv, 2005 Being the HIV-1 Protease (HIV-1-PR) an essential enzyme in the viral life cycle, its inhibition can control AIDS. The folding of single domain proteins, like each of the monomers forming the HIV-1-PR homodimer, is controlled by local elementary structures (LES, folding units stabilized by strongly interacting, highly conserved, as a rule hydrophobic ...
Abkevich +35 more
arxiv +3 more sources
Enzyme Inhibitors and Activators [PDF]
, 2017 Enzymes are very effective biological catalysts that accelerate almost all metabolic reactions in living organisms. Enzyme inhibitors and activators that modulate the velocity of enzymatic reactions play an important role in the regulation of metabolism.
O. Lopina
semanticscholar +11 more sources
Enzyme Inhibitors from Gorgonians and Soft Corals [PDF]
Marine Drugs, 2023 For decades, gorgonians and soft corals have been considered promising sources of bioactive compounds, attracting the interest of scientists from different fields. As the most abundant bioactive compounds within these organisms, terpenoids, steroids, and
Andrea Córdova-Isaza +3 more
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Enzyme Inhibitors as Multifaceted Tools in Medicine and Agriculture [PDF]
MoleculesEnzymes are molecules that play a crucial role in maintaining homeostasis and balance in all living organisms by catalyzing metabolic and cellular processes.
Sonia Del Prete, Mario Pagano
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Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective
Frontiers in Pharmacology, 2022 Angiotensin-converting enzyme (ACE), a zinc metalloprotein, is a central component of the renin–angiotensin system (RAS). It degrades bradykinin and other vasoactive peptides.
Wenyue Zheng +8 more
semanticscholar +1 more source
Exploration of Targeted Anti-tumor Therapy, 2023 Aim: Human histone deacetylase 8 (KDAC8) is a well-recognized pharmaceutical target in Cornelia de Lange syndrome and different types of cancer, particularly childhood neuroblastoma.
Markus Schweipert +2 more
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A Healthy and Ecologically Balanced Environment: An Argument for a Third Generation Right [PDF]
, 1993 Chymotrypsin-like serine proteases are found in high abundance in mast cell granules. By site-directed mutatgenesis, we have previously shown that basic amino acids in positions 143 and 192 (Arg and Lys respectively) of the human mast cell chymase are ...
Ahooghalandari, Parvin +5 more
core +15 more sources
Brazilian Archives of Biology and Technology, 2022 The genus Eucalyptus present high content of essential oil (EO). This study evaluated the pharmacological properties of Eucalyptus grandis (EG) and Eucalyptus microcorys (EM) EOs. The major component in both EOs was 1,8-Cineole.
Mariana Araújo Esposito +4 more
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Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Use of ACEIs (angiotensin-converting enzyme inhibitors) and ARBs (angiotensin II receptor blockers) is a major concern for clinicians treating coronavirus disease 2019 (COVID-19) in ...
Peng Zhang +43 more
semanticscholar +1 more source