Results 21 to 30 of about 713,685 (260)

Inhibition of antioxidant enzyme activities enhances carotenogenesis in microalga Dactylococcus dissociatus MT1

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Microalgal biotechnology has become a promising field of research for the production of valuable, sustainable and environmentally friendly byproducts, especially for carotenoids. Bulk accumulation of secondary carotenoids in microalgae are mostly induced
Nour Elaimane Bouzidi   +4 more
doaj   +1 more source

Immobilized enzyme reactors in HPLC and its application in inhibitor screening: A review

open access: yesJournal of Pharmaceutical Analysis, 2012
This paper sets out to summarize the literatures based on immobilized enzyme bio-chromatography and its application in inhibitors screening in the last decade.
Si-Meng Fang   +3 more
doaj   +1 more source

A comparative evaluation of NB30, NB54 and PTC124 in translational read‐through efficacy for treatment of an USH1C nonsense mutation

open access: yesEMBO Molecular Medicine, 2012
Translational read‐through‐inducing drugs (TRIDs) promote read‐through of nonsense mutations, placing them in the spotlight of current gene‐based therapeutic research.
Tobias Goldmann   +7 more
doaj   +1 more source

Harnessing the Bioactive Potential of Limonium spathulatum (Desf.) Kuntze: Insights into Enzyme Inhibition and Phytochemical Profile

open access: yesPlants, 2023
This study assessed the halophyte species Limonium spathulatum (Desf.) as a possible source of natural ingredients with the capacity to inhibit enzymes related to relevant human health disorders and food browning.
Seria Youssef   +7 more
doaj   +1 more source

The GDP-Mannose Dehydrogenase of Pseudomonas aeruginosa: An Old and New Target to Fight against Antibiotics Resistance of Mucoid Strains

open access: yesAntibiotics, 2023
Alginates play an important role in the resistance of mucoid strains of Pseudomonas aeruginosa to antibiotics, as well as their persistence by escaping the immune defense system.
Christian Hulen
doaj   +1 more source

Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors

open access: yesMolecules, 2018
We recently found that a cyclohexanecarboxamide derived from 4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-ene displayed low nanomolar inhibition of 11β-HSD1.
Rosana Leiva   +4 more
doaj   +1 more source

Impact of genetic variations on pharmacokinetic and pharmacodynamic properties of medicines and the future of drug therapy

open access: yesZanco Journal of Medical Sciences, 2020
Genetic variations between individuals usually leads to differences in the drug response as it could affect both pharmacokinetic and pharmacodynamic processes. An example of mutation of genes that affect drug targets (pharmacodynamic) is VKORC1 gene that
Rojgar Hamed Ali
doaj   +1 more source

A Review on Phyto-Therapeutic Approaches in Alzheimer’s Disease

open access: yesJournal of Functional Biomaterials, 2023
Neurodegenerative diseases occur due to progressive and sometimes irreversible loss of function and death of nerve cells. A great deal of effort is being made to understand the pathogenesis of neurodegenerative diseases.
Mehtap Sahiner   +3 more
doaj   +1 more source

A glimpse on biological activities of tellurium compounds

open access: yesAnais da Academia Brasileira de Ciências, 2009
Tellurium is a rare element which has been regarded as a toxic, non-essential trace element and its biological role is not clearly established to date. Besides of that, the biological effects of elemental tellurium and some of its inorganic and organic ...
Rodrigo L. O. R. Cunha   +2 more
doaj   +1 more source

INHIBITORS OF THE TRANSCRIBING ENZYMES [PDF]

open access: yesPure and Applied Chemistry, 1973
Abstract
openaire   +1 more source

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