Results 21 to 30 of about 2,078,222 (292)

A glimpse on biological activities of tellurium compounds

open access: yesAnais da Academia Brasileira de Ciências, 2009
Tellurium is a rare element which has been regarded as a toxic, non-essential trace element and its biological role is not clearly established to date. Besides of that, the biological effects of elemental tellurium and some of its inorganic and organic ...
Rodrigo L. O. R. Cunha   +2 more
doaj   +1 more source

The GDP-Mannose Dehydrogenase of Pseudomonas aeruginosa: An Old and New Target to Fight against Antibiotics Resistance of Mucoid Strains

open access: yesAntibiotics, 2023
Alginates play an important role in the resistance of mucoid strains of Pseudomonas aeruginosa to antibiotics, as well as their persistence by escaping the immune defense system.
Christian Hulen
doaj   +1 more source

Impact of genetic variations on pharmacokinetic and pharmacodynamic properties of medicines and the future of drug therapy

open access: yesZanco Journal of Medical Sciences, 2020
Genetic variations between individuals usually leads to differences in the drug response as it could affect both pharmacokinetic and pharmacodynamic processes. An example of mutation of genes that affect drug targets (pharmacodynamic) is VKORC1 gene that
Rojgar Hamed Ali
doaj   +1 more source

A Review on Phyto-Therapeutic Approaches in Alzheimer’s Disease

open access: yesJournal of Functional Biomaterials, 2023
Neurodegenerative diseases occur due to progressive and sometimes irreversible loss of function and death of nerve cells. A great deal of effort is being made to understand the pathogenesis of neurodegenerative diseases.
Mehtap Sahiner   +3 more
doaj   +1 more source

Evaluation Of Clinically Important Drug Interactions Involving Angiotensin-Converting Enzyme Inhibitors Among Cardiac Patients [QP609.A53 F219 2008 f rb]. [PDF]

open access: yes, 2008
Perencat penukar enzim angiotensin (ACEIs) telah digunakan secara meluas untuk merawat hipertensi dan penyakit kardiovaskular yang lain. Interaksi ubat-ACEI adalah merupakan masalah kesihatan yang signifikan dan perlu penyelidikan lanjut.
Amir Abdelkarim Farag, Omalhassan
core   +1 more source

Molecular Logic as a Means to Assess Therapeutic Antidotes

open access: yesFrontiers in Chemistry, 2019
An emerging direction in the area of molecular logic and computation is developing molecular-scale devices that can operate in complex biological environments, such as within living cells, which are beyond the reach of conventional electronic devices ...
Linor Unger-Angel   +2 more
doaj   +1 more source

The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Human carbonic anhydrase IX (CA IX), a protein specifically expressed on the surface of solid tumour cells, represents a validated target both for anticancer therapy and diagnostics.
Michael Kugler   +10 more
doaj   +1 more source

Eucalyptus grandis and Eucalyptus microcorys Essential Oils: in vitro Modulation of Hemostasis and Genotoxic Activity

open access: yesBrazilian Archives of Biology and Technology, 2022
The genus Eucalyptus present high content of essential oil (EO). This study evaluated the pharmacological properties of Eucalyptus grandis (EG) and Eucalyptus microcorys (EM) EOs. The major component in both EOs was 1,8-Cineole.
Mariana Araújo Esposito   +4 more
doaj   +1 more source

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
For over half a century, the carbazole skeleton has been the key structural motif of many biologically active compounds including natural and synthetic products.
Samar Issa   +6 more
doaj   +1 more source

Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum)

open access: yesAntioxidants, 2021
Seseli L. is one of the largest genera of the Apiaceae family widely known for their traditional uses as herbal remedies. In the present study, the methanolic and water extracts of two Seseli species, S. gummiferum and S.
Gokhan Zengin   +8 more
doaj   +1 more source

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