Results 11 to 20 of about 2,177,587 (253)
Angiotensin-converting Enzyme Inhibitors-induced Angioedema
Journal of Cardiovascular Emergencies, 2018 Angiotensin-converting enzyme inhibitors (ACEI) are widely used drugs nowadays in treating patients diagnosed with cardiovascular disorders. We present two consecutive cases of acquired angioedema caused by the administration of enalapril and lisinopril ...
Chiriac Anca +3 more
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Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]
, 2002 Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E. +5 more
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Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]
, 2013 Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C +24 more
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Exploration of Targeted Anti-tumor Therapy, 2023 Aim: Human histone deacetylase 8 (KDAC8) is a well-recognized pharmaceutical target in Cornelia de Lange syndrome and different types of cancer, particularly childhood neuroblastoma.
Markus Schweipert +2 more
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Nanozymes as Enzyme Inhibitors
International Journal of Nanomedicine, 2021 Yaling Huang,1 Jian Jiang,1 Yanqiu Wang,1 Jie Chen,1 Juqun Xi1,2 1Institute of Translational Medicine, Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, 225001, People’s Republic of China; 2Jiangsu Key ...
Huang Y, Jiang J, Wang Y, Chen J, Xi J
doaj
The structure of testis angiotensin-converting enzyme (tACE-g13) in complex with the inhibitor RXPA380 [PDF]
, 2006 Includes bibliographical references.Angiotensin-converting enzyme (ACE), a zinc metalloprotease, is a key regulator of the mammalian renin-angiotensin system (RAS) Primarily, ACF is a dipeptidl peptidase which cleaves angiotensin I to produce angiotensin
Chitapi, Itai
core +1 more source
Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors
Molecules, 2018 We recently found that a cyclohexanecarboxamide derived from 4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-ene displayed low nanomolar inhibition of 11β-HSD1.
Rosana Leiva +4 more
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Plants, 2023 This study assessed the halophyte species Limonium spathulatum (Desf.) as a possible source of natural ingredients with the capacity to inhibit enzymes related to relevant human health disorders and food browning.
Seria Youssef +7 more
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A glimpse on biological activities of tellurium compounds
Anais da Academia Brasileira de Ciências, 2009 Tellurium is a rare element which has been regarded as a toxic, non-essential trace element and its biological role is not clearly established to date. Besides of that, the biological effects of elemental tellurium and some of its inorganic and organic ...
Rodrigo L. O. R. Cunha +2 more
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Antibiotics, 2023 Alginates play an important role in the resistance of mucoid strains of Pseudomonas aeruginosa to antibiotics, as well as their persistence by escaping the immune defense system.
Christian Hulen
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