Results 161 to 170 of about 8,754,571 (337)

Evaluation of Enzyme Inhibitory Activity of Flavonoids by Polydopamine-Modified Hollow Fiber-Immobilized Xanthine Oxidase. [PDF]

Molecules, 2021
Zhao CP, Chen GY, Wang Y, Chen H, Yu JW, Yang FQ.   +5 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Analysis of Angiotensin I Converting Enzyme Inhibitory Activity of Oligosacchride Extracted from Capsosiphon fulvescens

, 2013
© 2013 The Korean Society for Biotechnology and Bioengineering Abstract: The hydrolysates prepared with various enzyme digestion of Capsosiphon fulvescens were used to measure the inhibitory effects against angiotensin I converting enzyme (ACE).
Jung-heon Lee, Hyun-woo Kim
core  

Inhibitory effects of ofloxacin and cefepime on enzyme activity of 6-phosphogluconate dehydrogrenase from chicken liver

, 2007
In this study, effects of some antibiotics, namely, ofloxacin, cefepime, cefazolin, and ampicillin on the in vitro enzyme activity of 6-phosphogluconate dehydrogenase have been investigated. For this purpose, 6-phosphogluconate dehydrogenase was purified
Erat, MUSTAFA, Sakiroglu, Halis
core   +1 more source

Tyrosinase Enzyme Inhibitory Activity Assay Of Ethanol Extract Of Pirdot Leaves (Saurauia vulcani Korth.)

Background: Materials used to overcome hyperpigmentation often caused side effects. Therefore, natural materials were needed to address hyperpigmentation while minimizing those side effects.
Barus, Silvyani Agustilova
core   +1 more source

The Inhibition of Pancreatic α-Amylase by Monomeric, Dimeric and Trimeric Procyanidins Is Dependent upon the Structural Characteristics of Inhibitors and Substrates

Applied Biosciences
Procyanidins are oligomeric flavonoids with several bioactive properties. Their antidiabetic potential is related to their capacity to inhibit enzymes responsible for the absorption of dietary carbohydrates, such as pancreatic α-amylase.
Jocelin Violeta Aguilar-López, Ana V. Arras-Gardea, Alejandra I. Martinez-Gonzalez, Emilio Alvarez-Parrilla, Laura A. de la Rosa   +4 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Synthesis of N-Substituted Glucosamine Derivatives and Their Angiotensin I Converting Enzyme Inhibitory Activity [PDF]

Inhibitory activity of glucosamine derivatives against angiotensin I converting enzyme (ACE) was investigated. Many N-substituted glucosamine derivatives were synthesized via 1,3,4,6-tetra-O-acetyl-glucosamine hydrochloride.
Ajiro, H, Tadasa, K, Kawakami, A, Kayahara, H   +3 more
core   +1 more source

Therapeutic Potential of a Novel Vitamin D₃ Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding. [PDF]

Biomolecules, 2022
Alshabrawy AK, Cui Y, Sylvester C, Yang D, Petito ES, Barratt KR, Sawyer RK, Heatlie JK, Polara R, Sykes MJ, Atkins GJ, Hickey SM, Wiese MD, Stringer AM, Liu Z, Anderson PH.   +15 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source