Results 81 to 90 of about 8,754,571 (337)

Alkaloids from Stephania cephalantha and their enzyme inhibitory activities

Natural Product Research
A new protoberberine type alkaloid, 11-diethylaminomethyl corydalmine (1), and 27 known alkaloids (2-28) were isolated from the tuberous roots of Stephania cephalantha. Their structures were identified by spectral analysis. Enzyme inhibitory activities of the compounds on acetylcholinesterase (AChE), tyrosinase and α-glucosidase were evaluated ...
Long-Fen, Luo, Ming-Ming, Tian, Ji-Chun, Wu   +2 more
openaire   +2 more sources

Angiotensin I Converting Enzyme Inhibitory Activities of Various Fermented Foods

Bioscience, Biotechnology, and Biochemistry, 1995
Angiotensin I converting enzyme (ACE, E.C. 3.4.15.1) inhibitory activity were measured with 11 kinds (31 items) of fermented foods. Strong inhibitory activity was detected in soy sauce, fish sauce, natto, nyufu, and cheese, but not in mirin, sake, or vinegar.
Okamoto, Akiko, Hanagata, Hiroshi, Matsumoto, Eiko, Kawamura, Yukio, Koizumi, Yukimichi, Yanagida, Fujiharu   +5 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Captopril molecules exhibit significant inhibitory effect for peroxidase-like nitrogendoped carbon dots [PDF]

, 2023
In this continuation, the inhibitory effect of captopril molecules on the nanozymatic activity of peroxidase-like nitrogen-doped carbon dots was evaluated.
Saeed Reza, Hormozi Jangi
core   +1 more source

Comprehensive analysis of metabolite accumulation and activity changes in Opisthopappus taihangensis during different developmental stages

Scientia Horticulturae
Despite extensive research on the health benefits of chrysanthemum, much remains unknown about chemical composition and health benefits of Taihang chrysanthemum (Opisthopappus taihangensis), especially how they vary during growth.
Xiran Xiong, Dongge Fan, Jinnan Zhang, Pinjie Lu, Qing Yuan, Yanlong Zhang, Xiaoxiao Zhang   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Assessment of in vitro alpha-glucosidase inhibitory activity, phenolics, flavonoidsand antioxidant potential of jamun (Syzygium cumini) seeds

Journal of Horticultural Sciences
Jamun (Syzygium cumini Linn. Syn. Eugenia jambolana) genotypes collected from different parts of the country were evaluated for in vitro alpha-glucosidase inhibitory activity, polyphenolic content and antioxidant potential along with fruit characters ...
Arivalagan M, Priyanka DR, Rekha A, Tripathi PC   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Enzyme inhibitory effect and antioxidant properties of astragalus lagurus extracts

, 2016
Antioxidant and enzyme inhibitory effects (against cholinesterase, tyrosinase, ?-amylase and ?-glucosidase) of ethyl acetate, methanol, and aqueous extracts from Astragalus lagurus (Fabaceae) were investigated with spectrophotometric methods. Antioxidant
Ceylan, Ramazan, Zengin, Gokhan, Guler, Gokalp O., Carradori, S., Uysal, Sengul, Güler, Gökalp Özmen, Aktumsek, Abdurrahman, Carradori, Simone   +7 more
core   +1 more source