Results 261 to 270 of about 1,224,230 (307)

A molluscan peptide α‐amidating enzyme precursor that generates five distinct enzymes

The FASEB Journal, 1999
Mechanisms underlying the specificity and efficiency of enzymes, which modify peptide messengers, especially with the variable requirements of synthesis in the neuronal secretory pathway, are poorly understood. Here, we examine the process of peptide α‐amidation in individually identifiable Lymnaea
Spijker, S., Smit, A.B., Eipper, B.A., Malik, A., Mains, R.E., Geraerts, W.P.M.   +5 more
openaire   +3 more sources

Opioid and tachykinin peptides, and their precursors and precursor-processing enzymes, in human cerebrospinal fluid

Journal of Chromatography A, 1990
Opioid and tachykinin neuropeptides, which were derived from two biological sources (intact, and released from their corresponding precursors by the action of human cerebrospinal fluid (CSF) neuropeptidases), were characterized in human CSF by using a combination of post-high-performance liquid chromatographic (HPLC) detection techniques. Peptides were
D X, Liu, C, Dass, G, Wood, D M, Desiderio   +3 more
openaire   +2 more sources

A unique vacuolar processing enzyme responsible for conversion of several proprotein precursors into the mature forms [PDF]

FEBS Letters, 1991
Proprotein precursors of vacuolar components are transported from the endoplasmic reticulum into vacuoles, where they are proteolytically processed into their mature forms.
Mikio Nishimura, Ikuko Hara-Nishimura
exaly   +2 more sources

Ornithine transcarbamylase deficiency with a truncated enzyme precursor

Journal of Inherited Metabolic Disease, 1987
Ornithine transcarbamylase (OTC, EC 2.1.3.3), located in the mitochondriat matrix, is synthesized on membrane-free polysomes in the form of a larger precursor and is then proteolytically processed to the mature form. OTC deficiency, which is a disease with X-linked dominant inheritance, is caused by various kinds of mutation (Briand et al., 1982).
H. Kodama, I. Okabe, A. Ohtake, M. Mori
openaire   +1 more source

Enzymic routes to dihydroxyacetone phosphate or immediate precursors

Journal of Molecular Catalysis B: Enzymatic, 2002
Dihydroxyacetone phosphate (DHAP) is an important substrate for enzymic syntheses of saccharides by means of dihydroxyacetone phosphate aldolases. A convenient precursor of DHAP is L-glycerol-3-phosphate (L-G3P), the enzymic synthesis of which may be achieved by phosphate transfer owing to an ATP-regenerating system.
Hettwer, J, Oldenburg, H, Flaschel, Erwin   +2 more
openaire   +2 more sources

A general method for the rapid measurement of enzyme precursors by the displacement of enzyme from antibody: The measurement of collagen proline hydroxylase precursor in cultured fibroblasts

Biochemical and Biophysical Research Communications, 1972
Abstract A method has been developed for measuring inactive forms of an enzyme by displacing active enzyme from its antibody. The unbound enzyme is measured by an enzymatic assay. The method has been applied to the measurement of the precursor of collagen proline hydroxylase in cultured fibroblasts.
J O, McGee, S, Udenfriend
openaire   +2 more sources

Enzyme Organization in DNA Precursor Biosynthesis

1993
Publisher Summary This chapter discusses the process by which DNA precursors are synthesized and delivered to replication sites and consider the possibility of physical or functional linkage between enzymes of deoxyribonucleoside 5‘-triphosphate (dNTP)’ synthesis and those directly involved in the replication.
openaire   +2 more sources

Photoactive pigment—enzyme complexes of chlorophyll precursor in plant leaves

Biochemistry (Moscow), 2007
This review summarizes contemporary data on structure and function of photoactive pigment--enzyme complexes of the chlorophyll precursor that undergoes photochemical transformation to chlorophyllide. The properties and functions of the complex and its principal components are considered including the pigment (protochlorophyllide), the hydrogen donor ...
O B, Belyaeva, F F, Litvin
openaire   +2 more sources

[5] Overexpression of neuropeptide precursors and processing enzymes

1995
Publisher Summary This chapter discusses the overexpression of neuropeptide precursors and processing enzymes. It is reported that the dihydrofolate reductase (DHFR)-coupled amplification method is a reliable and relatively straightforward way to overexpress a variety of different protein precursors.
Iris Lindberg, Yi Zhou
openaire   +1 more source

Proteolytic enzymes in the post-translational processing of polypeptide hormone precursors

Neurochemical Research, 1987
Selective and limited proteolysis is a key step in the post-translational modification of peptide hormone precursors. This process appears to involve a proteolytic machinery including highly specific endoproteases. Some of the enzyme systems possibly involved in the processing of pro-neuropeptides will be described and their mechanism of action ...
P, Gluschankof, P, Cohen
openaire   +2 more sources