Results 31 to 40 of about 2,217,916 (339)
TIGHT REPRESSION OF ELASTASE STRAIN K OVEREXPRESSION BY PT7 (A1/O4/O3) SHUTTLE EXPRESSION SYSTEM [PDF]
Science Heritage Journal, 2017 The PT7(A1/O4/O3) is a promoter resulted from construction of O3 and O4 operators into PA1, a promoter derived from coliphage T7, that evidenced lower the occupancy of the promoter by RNA polymerase and thereby increases the repression factor.
Nurul Hazwani +3 more
doaj +1 more source
Biotechnology for Biofuels and Bioproducts, 2023 Background Filamentous fungi possess an array of secreted enzymes to depolymerize the structural polysaccharide components of plant biomass. Sugar transporters play an essential role in nutrient uptake and sensing of extracellular signal molecules to ...
Shuying Gu +6 more
doaj +1 more source
Nature Communications, 2020 Polyamine metabolism is frequently dysregulated in cancers. Here, the authors show that a polyamine biosynthetic enzyme, spermine synthase, is overexpressed in colorectal cancers and cooperates with MYC to prevent cancer cell apoptosis by repression of ...
Yubin Guo +13 more
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LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing Catalase
Cells, 2021 The increased level of hydrogen peroxide accompanies some modes of macrophage specification and is linked to ROS-based antimicrobial activity of these phagocytes.
Maciej Sobczak +5 more
doaj +1 more source
Biotechnology for Biofuels, 2021 Background Cellulolytic enzyme production in filamentous fungi requires a release from carbon catabolite repression (CCR). The protein CRE1/CreA (CRE = catabolite responsive element) is a key transcription factor (TF) that is involved in CCR and ...
Yueyan Hu +5 more
doaj +1 more source
Biotechnology for Biofuels, 2019 Background Enzymatic hydrolysis of lignocellulose by fungi is a key step in global carbon cycle and biomass utilization. Cellulolytic enzyme production is tightly controlled at a transcriptional level. Here, we investigated the roles of different histone
Yanan Li +8 more
doaj +1 more source
Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p. [PDF]
PLoS Biology, 2010 Intron-containing pre-mRNAs are normally retained and processed in the nucleus but are sometimes exported to the cytoplasm and degraded by the nonsense-mediated mRNA decay (NMD) pathway as a consequence of their inclusion of intronic in-frame termination
Shuyun Dong, Allan Jacobson, Feng He
doaj +1 more source
Brazilian Archives of Biology and Technology, 2009 Effects of xylose on xylanase production by a thermophilic Bacillus sp showed diverse patterns on corn cob (CC) and wheat bran (WB) as sole carbon sources in solid- state fermentation (SSF) and submerged fermentation (SmF). Supplementation of these media
Uma Gupta, Rita Kar
doaj +1 more source
Nonequilibrium model of short-range repression in gene transcription regulation [PDF]
Phys. Rev. E 104, 014407 (2021), 2020 Transcription factors are proteins that regulate gene activity by activating or repressing gene transcription. A special class of transcriptional repressors operates via a short-range mechanism, making local DNA regions inaccessible to binding by activators, and thus providing an indirect repressive action on the target gene. This mechanism is commonly
arxiv +1 more source
Scientific Reports, 2021 Female puberty is subject to Polycomb Group (PcG)-dependent transcriptional repression. Kiss1, a puberty-activating gene, is a key target of this silencing mechanism.
Hollis Wright +4 more
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