Results 31 to 40 of about 108,982 (307)
Scd6 protein family members are evolutionarily conserved components of translationally silent mRNA granules. Yeast Scd6 interacts with Dcp2 and Dhh1, respectively a subunit and a regulator of the mRNA decapping enzyme, and also associates with ...
Quira Zeidan +5 more
doaj +1 more source
Background Pluripotency, the capacity for indefinite self-renewal and differentiation into diverse cell types is a unique state exhibited by embryonic stem (ES) cells.
Yeap Leng-Siew +2 more
doaj +1 more source
The Methyltransferase Setd8 Is Essential for Erythroblast Survival and Maturation
Erythropoiesis is a highly regulated process that generates enucleate red blood cells from committed erythroid progenitors. Chromatin condensation culminating in enucleation is a defining feature of this process.
Jeffrey Malik +4 more
doaj +1 more source
Investigation of bacterial gene regulation upon environmental changes is still a challenging task. For example, Vibrio cholerae, a pathogen of the human gastrointestinal tract, faces diverse transient conditions in different compartments upon oral ...
Franz Zingl +3 more
doaj +1 more source
Phytochrome-Mediated Repression of Enzyme Synthesis (Lipoxygenase): A Threshold Phenomenon [PDF]
Synthesis of the enzyme lipoxygenase in the cotyledons of the mustard seedling ( Sinapis alba L. ) is controlled by phytochrome ( P fr ) through a threshold mechanism. The repression of enzyme synthesis by P fr
H, Oelze-Karow, P, Schopfer, H, Mohr
openaire +2 more sources
A Peroxisomal Lon Protease and Peroxisome Degradation by Autophagy Play Key Roles in Vitality of Hansenula polymorpha Cells [PDF]
In eukaryote cells various mechanisms exist that are responsible for the removal of non-functional proteins. Here we show that in the yeast Hansenula polymorpha (H.
Bener Aksam, Eda +5 more
core +2 more sources
Pseudouridylate Synthetase of Escherichia coli: a Catabolite-Repressible Enzyme [PDF]
The growth on pseudouridine of two pyrimidine auxotrophs of Escherichia coli (Bu − and W63-86) was markedly enhanced when glycerol replaced glucose as a carbon source or when adenosine 3′:5′-cyclic monophosphoric acid was added to medium containing glucose.
L R, Solomon, T R, Breitman
openaire +2 more sources
Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C. +3 more
core +4 more sources
Transcriptional Repression of Catalase in Mouse Skin Tumor Progression
Previous studies in our laboratory have shown that the elevation of reactive oxygen species levels and the repression of the antioxidant enzyme, catalase, played a critical role in the in vitro progression of benign papilloma cells to malignant carcinoma
Kevin A. Kwei +3 more
doaj +1 more source
The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression. [PDF]
PR-Set7/Set8/KMT5a is a chromatin-modifying enzyme that specifically monomethylates lysine 20 of histone H4 (H4K20me1). In this study we attempted to identify PR-Set7-interacting proteins reasoning that these proteins would provide important insights ...
Tanya M Spektor +3 more
doaj +1 more source

