Results 31 to 40 of about 108,982 (307)

Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo.

open access: yesPLoS Genetics, 2018
Scd6 protein family members are evolutionarily conserved components of translationally silent mRNA granules. Yeast Scd6 interacts with Dcp2 and Dhh1, respectively a subunit and a regulator of the mRNA decapping enzyme, and also associates with ...
Quira Zeidan   +5 more
doaj   +1 more source

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage

open access: yesEpigenetics & Chromatin, 2009
Background Pluripotency, the capacity for indefinite self-renewal and differentiation into diverse cell types is a unique state exhibited by embryonic stem (ES) cells.
Yeap Leng-Siew   +2 more
doaj   +1 more source

The Methyltransferase Setd8 Is Essential for Erythroblast Survival and Maturation

open access: yesCell Reports, 2017
Erythropoiesis is a highly regulated process that generates enucleate red blood cells from committed erythroid progenitors. Chromatin condensation culminating in enucleation is a defining feature of this process.
Jeffrey Malik   +4 more
doaj   +1 more source

TetR Regulated in vivo Repression Technology to Identify Conditional Gene Silencing in Genetically Engineerable Bacteria Using Vibrio cholerae Murine Infections as Model System

open access: yesBio-Protocol, 2020
Investigation of bacterial gene regulation upon environmental changes is still a challenging task. For example, Vibrio cholerae, a pathogen of the human gastrointestinal tract, faces diverse transient conditions in different compartments upon oral ...
Franz Zingl   +3 more
doaj   +1 more source

Phytochrome-Mediated Repression of Enzyme Synthesis (Lipoxygenase): A Threshold Phenomenon [PDF]

open access: yesProceedings of the National Academy of Sciences, 1970
Synthesis of the enzyme lipoxygenase in the cotyledons of the mustard seedling ( Sinapis alba L. ) is controlled by phytochrome ( P fr ) through a threshold mechanism. The repression of enzyme synthesis by P fr
H, Oelze-Karow, P, Schopfer, H, Mohr
openaire   +2 more sources

A Peroxisomal Lon Protease and Peroxisome Degradation by Autophagy Play Key Roles in Vitality of Hansenula polymorpha Cells [PDF]

open access: yes, 2007
In eukaryote cells various mechanisms exist that are responsible for the removal of non-functional proteins. Here we show that in the yeast Hansenula polymorpha (H.
Bener Aksam, Eda   +5 more
core   +2 more sources

Pseudouridylate Synthetase of Escherichia coli: a Catabolite-Repressible Enzyme [PDF]

open access: yesJournal of Bacteriology, 1971
The growth on pseudouridine of two pyrimidine auxotrophs of Escherichia coli (Bu − and W63-86) was markedly enhanced when glycerol replaced glucose as a carbon source or when adenosine 3′:5′-cyclic monophosphoric acid was added to medium containing glucose.
L R, Solomon, T R, Breitman
openaire   +2 more sources

Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]

open access: yes, 2006
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C.   +3 more
core   +4 more sources

Transcriptional Repression of Catalase in Mouse Skin Tumor Progression

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
Previous studies in our laboratory have shown that the elevation of reactive oxygen species levels and the repression of the antioxidant enzyme, catalase, played a critical role in the in vitro progression of benign papilloma cells to malignant carcinoma
Kevin A. Kwei   +3 more
doaj   +1 more source

The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression. [PDF]

open access: yesPLoS ONE, 2011
PR-Set7/Set8/KMT5a is a chromatin-modifying enzyme that specifically monomethylates lysine 20 of histone H4 (H4K20me1). In this study we attempted to identify PR-Set7-interacting proteins reasoning that these proteins would provide important insights ...
Tanya M Spektor   +3 more
doaj   +1 more source

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