Results 121 to 130 of about 5,877,636 (396)

A novel enzymatic approach to nanocrystalline cellulose preparation [PDF]

open access: yes, 2018
In this work, conditions for an enzymatic pretreatment prior to NCC isolation from cotton linter were assessed. Different cellulase doses and reaction times were studied within an experimental design and NCC were obtained. At optimal enzymatic conditions
Beltramino, Facundo   +3 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Immobilization Techniques for Food-Grade Nuclease P1 and Their Application in Nucleotide Production

open access: yesFoods
Nuclease P1 (NP1) is critical for producing 5′-nucleotides, which are essential flavor enhancers in the food industry. Traditional use of free NP1 is hampered by poor reusability, high costs, and potential residual enzyme protein contamination ...
Xiao-Yan Yin   +3 more
doaj   +1 more source

Research Progress in Enzyme Engineering Strategies to Improve the Thermal Stability of Enzymatic Time-Temperature Indicators [PDF]

open access: yesShipin Kexue
Food safety is paramount to the health of consumers. Enzymatic time-temperature indicators are capable of monitoring the cumulative heat exposure after the production of food products and providing visual color changes indicative of product shelf life ...
PENG Huakang, ZHANG Huanzhi, WANG Chenyue, WANG Yao
doaj   +1 more source

Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering

open access: yesACS Central Science
Enzymes can be engineered at the level of their amino acid sequences to optimize key properties such as expression, stability, substrate range, and catalytic efficiency—or even to unlock new catalytic activities not found in nature.
Jason Yang   +2 more
semanticscholar   +1 more source

Fully Integrated Biochip Platforms for Advanced Healthcare [PDF]

open access: yes, 2012
Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers.
Baj-Rossi, Camilla   +11 more
core   +5 more sources

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