Results 21 to 30 of about 560,659 (266)

Engineering Enhanced Antimicrobial Properties in α-Conotoxin RgIA through D-Type Amino Acid Substitution and Incorporation of Lysine and Leucine Residues

Molecules
Antimicrobial peptides (AMPs), acknowledged as host defense peptides, constitute a category of predominant cationic peptides prevalent in diverse life forms. This study explored the antibacterial activity of α-conotoxin RgIA, and to enhance its stability
Minghe Wang, Zhouyuji Liao, Dongting Zhangsun, Yong Wu, Sulan Luo   +4 more
doaj   +1 more source

Stabilization of the Cellulase Enzyme Complex as Enzyme Nanoparticle

Applied Biochemistry and Biotechnology, 2012
The native Celluclast BG cellulase enzyme complex consists of different enzymes which can also degrade great substrate molecules as native celluloses. This enzyme complex has been covered by a very thin, a few nanometers thick, polymer layer, in order to improve its stability.
Hegedues, Imre, Hancsok, Jeno, Nagy, Endre   +2 more
openaire   +3 more sources

The development of human sera tests for HDL-bound serum PON1 and its lipolactonase activitys⃞

Journal of Lipid Research, 2007
Serum paraoxonase (PON1) is a lipolactonase that associates with HDL-apolipoprotein A-I (HDL-apoA-I) and thereby plays a role in the prevention of atherosclerosis. Current sera tests make use of promiscuous substrates and provide no indications regarding
Leonid Gaidukov, Dan S. Tawfik
doaj   +1 more source

Production of extracellular protease by a Brazilian strain of Beauveria bassiana reactivated on coffee berry borer, Hypothenemus hampei

Brazilian Archives of Biology and Technology, 2007
Studies were carried out on extracellular protease production by Beauveria bassiana CG432 in liquid medium containing glucose and yeast extract. B. Bassiana presented active growth after lag period of 24 h., produced 80% of the total of the extracellular
Eliana Tiemi Ito, Geni Varéa-Pereira, Dalva Tomoe Miyagui, Maria Helena Pimenta Pinotti, Pedro Manoel Oliveira Janeiro Neves   +4 more
doaj   +1 more source

Tablet-Based Sensor: A Stable and User-Friendly Tool for Point-of-Care Detection of Glucose in Urine

Biosensors, 2023
The colorimetric detection of glucose in urine through enzymatic reactions offers a low-cost and non-invasive method to aid in diabetes management. Nonetheless, the vulnerability of enzymes to environmental conditions, particularly elevated temperatures,
Hasti Hajimiri, Seyed Hamid Safiabadi Tali, Muna Al-Kassawneh, Zubi Sadiq, Sana Jahanshahi-Anbuhi   +4 more
doaj   +1 more source

Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design

Drug Delivery, 2022
The lipophilicity of a peptide drug can be considerably increased by hydrophobic ion pairing with amphiphilic counterions for successful incorporation into lipid-based formulations.
Yoon Tae Goo, Sangkil Lee, Ji Yeh Choi, Min Song Kim, Gi Hyeong Sin, Sun Ho Hong, Chang Hyun Kim, Seh Hyon Song, Young Wook Choi   +8 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Enzyme-Assisted Extraction of Bioactive Compounds from Rosa canina L. Pseudofruit in Natural Deep Eutectic Solvents: Protease Stability and Biological Activities

Plants
Enzyme-Assisted Extraction (EAE) in Natural Deep Eutectic Solvents (NaDES) was investigated as a green approach to extract bioactive compounds from the pseudofruit of Rosa canina L.
Lemoni Zafeiria, Tzani Andromachi, Karagianni Alexandra, Stavropoulos Georgios, Lymperopoulou Theopisti, Alexandratou Eleni, Detsi Anastasia, Mamma Diomi   +7 more
doaj   +1 more source

Escherichia coli Fails to Efficiently Maintain the Activity of an Important Flavin Monooxygenase in Recombinant Overexpression

Frontiers in Microbiology, 2017
This paper describes the measurement and analysis of in vivo activity and stability of cyclohexanone monooxygenase from Acinetobacter sp. NCIMB 9871 (CHMO), a model Baeyer–Villiger monooxygenase, in the recombinant host Escherichia coli.
Sofia Milker, Leticia C. P. Goncalves, Michael J. Fink, Michael J. Fink, Florian Rudroff   +4 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source