Results 1 to 10 of about 784,273 (205)
Opportunities for nanomaterials in enzyme therapy [PDF]
Journal of Controlled ReleaseIn recent years, enzyme therapy strategies have rapidly evolved to catalyze essential biochemical reactions with therapeutic potential. These approaches hold particular promise in addressing rare genetic disorders, cancer treatment, neurodegenerative conditions, wound healing, inflammation management, and infectious disease control, among others. There
BEATRIZ Torres Herrero +2 more
exaly +7 more sources
Enzyme therapy in a structural light [PDF]
IUCrJThe paper by Gilski et al. in this issue [IUCrJ (2026), 13, 132–145] focuses on the stereochemical analysis of the catalytic mechanism of asparaginases with the aim of resolving key ambiguities in the mechanism.
Jon Cooper
doaj +2 more sources
Pancreatic enzyme therapy. [PDF]
Dtsch Arztebl Int, 2010 Treatment with pancreatic enzymes must be based on an understanding of the normal physiology and pathophysiology of exocrine pancreatic function, as well as of the diseases that cause exocrine pancreatic insufficiency of either a structural or a functional type.
Mössner J, Keim V.
europepmc +4 more sources
Kinetics of MSC-based enzyme therapy for immunoregulation [PDF]
Journal of Translational Medicine, 2019 Background Mesenchymal stromal cells (MSC) demonstrate innate and regulatory immunologic functions and have been widely explored for cell therapy applications.
Alexandra Burr, Biju Parekkadan
doaj +2 more sources
Substrate mediated enzyme prodrug therapy. [PDF]
PLoS ONE, 2012 In this report, we detail Substrate Mediated Enzyme Prodrug Therapy (SMEPT) as a novel approach in drug delivery which relies on enzyme-functionalized cell culture substrates to achieve a localized conversion of benign prodrug(s) into active therapeutics
Betina Fejerskov, Alexander N Zelikin
doaj +4 more sources
The effectiveness of systemic enzyme therapy in complex treatment chronic pancreatitis in old age
Journal of Education, Health and Sport, 2021 Relevance. The variety of functional changes in internal organs characteristicofgeriatricage necessitates the search for drugs that can exert a multifaceted effect on various links in the pathogenesis of chronic pancreatitis (CP) in comorbidity with the ...
N. A. Shevchenko, L. S. Babinets
doaj +1 more source
Сибирский научный медицинский журнал, 2023 One of the serious intra-abdominal complications after surgery is intestinal obstruction of adhesion origin (IOAO). Mortality during postoperative intestinal obstruction is 16.2–52.5 %.
I. A. Yusubov
doaj +1 more source
Clinical and laboratory efficacy of systemic enzyme therapy in patients with chronic generalized periodontitis complicated by purulent foci in soft periodontal tissues [PDF]
Medičnì Perspektivi, 2017 The article presents the results of complex treatment of 98 patients with chronic generalized periodontitis with purulent foci in periodontal tissues by using standard complex treatment in combination with systemic enzyme therapy, which in turn allows to
Gudaryan А.А. +2 more
doaj +3 more sources
Nanomaterials, 2022 Enzyme therapy has important implications for the treatment of metabolic disorders and biological detoxification. It remains challenging to prepare enzymatic nanoreactors with high therapeutic efficiency and low emission of cytotoxic reaction ...
Chao Deng +3 more
doaj +1 more source
Pharmaceutics, 2021 To date, there is no effective treatment for celiac disease (CD, gluten enteropathy), an autoimmune disease caused by gluten-containing food. Celiac patients are supported by a strict gluten-free diet (GFD).
Yakov E. Dunaevsky +5 more
doaj +1 more source