Results 21 to 30 of about 784,273 (205)

EVALUATION OF THE EFFICIENCY OF COMBINATION THERAPY WITH HYALURONATES IN PATIENTS WITH HIP OSTEOARTHROSIS

Научно-практическая ревматология, 2011
Objective: to make the results of treatment for coxarthrosis better via prosthetic synovial fluid replacement, by improving drug delivery into the joint cavity. Subjects and methods. The clinical trial enrolled 359 outpatients treated for coxarthrosis. A
A G Shusharin, V M Prokhorenko, V V Morozov, A I Shevela   +3 more
doaj   +1 more source

NEUROINFECTIOUS DISEASES IN CHILDREN

Детские инфекции (Москва), 2015
The article presents the results of many years of work of the Department of Neuroinfections and Organic Pathology of Nervous System on diagnostics and treatment of children with infectious diseases affecting nervous system.
N. V. Skripchenko, V. V. Lobzin, G. P. Ivanova, V. N. Komantsev, L. A. Alekseeva, M. V. Ivanova, A. A. Vilnits, E. Yu. Gorelik, E. Yu. Skripchenko   +8 more
doaj   +1 more source

Economic barriers restraining the production of therapeutic recombinant human trypsin. Use of innovative technologies to overcome them

Фармакоэкономика, 2018
The aim of this review is to analyze reasons for the high cost of recombinant human trypsin, technological and economic obstacles limiting trypsin production and implementation, as well as practical means to solve these problems.Materials and methods ...
S. V. Ponomarenko
doaj   +1 more source

Lactase deficiency and gastrointestinal allergies in young children

Медицинский совет, 2020
Intestinal colic, food allergies are one of the common causes of the initial treatment of children in their first year of life in outpatient practice. Gastrointestinal allergy is a lesion of the gastrointestinal tract of an allergic nature, is in second ...
N. V. Ziatdinova, T. G. Malanicheva, L. A. Bareeva   +2 more
doaj   +1 more source

MODERN VIEWS ON ETIOLOGY OF CHRONIC PANCREATITIS AND CORRECTION OF FUNCTIONAL INSUFFICIENCY OF THE PANCREAS

Вопросы современной педиатрии, 2012
Chronic pancreatitis is a multietiological disorder characterized by progressive structural changes of the pancreas and development of its eccrine and endocrine insufficiency.
E. А. Kornienko, A. A. Yagupova
doaj   +1 more source

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds [PDF]

, 2013
This work was supported by a Wellcome Trust award to TMG.Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this ...
Brooks, Doug, Gloster, Tracey M., Vocadlo, D.J., Brooks, D., Kolarich, Daniel, Kermode, Allison R, Kermode, Allison R., Haselhorst, T., Qian, Y., Gloster, Tracey M, Qian, Yi, Gloster, Tracey, Kolarich, D., Haselhorst, Thomas, Packer, N.H., Pierce, Owen, He, X., von Itzstein, Mark, Gloster, T.M., Packer, Nicolle H., He, Xu, Pierce, O., Packer, Nicolle H, Vocadlo, David J, von Itzstein, M., Kermode, A.R., Vocadlo, David J.   +26 more
core   +1 more source

Enzyme-replacement therapy for hypophosphatasia

BoneKEy Reports, 2012
Hypophosphatasia (HPP) is associated with significant morbidity and mortality in pediatric patients. The disease also imposes a high disease-burden in adult-onset HPP. Asfotase alfa (AA) is the first-in-class, bone-targeted, enzyme- replacement therapy designated to reverse the skeletal mineralisation defects in HPP.
S. Ahmet, Uçaktürk, Selin, Elmaogullari, Sevim, Ünal, Deniz, Gönülal, Eda, Mengen   +4 more
openaire   +5 more sources

Current and Future Therapeutic Approaches of Exocrine Pancreatic Insufficiency in Children with Cystic Fibrosis in the Era of Personalized Medicine

Pharmaceutics, 2023
This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of ...
Mirela-Elena Ritivoiu, Cristina Manuela Drăgoi, Dumitru Matei, Iustina Violeta Stan, Alina Crenguţa Nicolae, Mihai Craiu, Ion-Bogdan Dumitrescu, Alina Angelica Ciolpan   +7 more
doaj   +1 more source

Fifteen years of enzyme replacement therapy for mucopolysaccharidosis type VI (Maroteaux–Lamy syndrome): a case report

Journal of Medical Case Reports, 2022
Background Mucopolysaccharidosis VI, or Maroteaux–Lamy disease, is an autosomal recessive disease characterized by deficiency of the enzyme arylsulfatase B in the lysosomal catabolism of glycosaminoglycans.
Isadora Andrade, River Ribeiro, Zumira A. Carneiro, Roberto Giugliani, Catarina Pereira, Claudia Cozma, Daniel Grinberg, Lluïsa Vilageliu, Charles M. Lourenco   +8 more
doaj   +1 more source

The Adaptable Binding Cleft of RmuAP1, a Pepsin-like Peptidase from Rhodotorula mucilaginosa, Enables the Enzyme to Degrade Immunogenic Peptides Derived from Gluten

Biomolecules
Celiac disease (CD) is an autoimmune disorder triggered by pepsin-resistant, gluten-derived immunogenic peptides (GIPs) in genetically predisposed individuals.
Yu-Han Zhang, Chia-Liang Lin, Menghsiao Meng   +2 more
doaj   +1 more source