Results 91 to 100 of about 2,144,314 (302)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The effects of inorganic salts on biosynthesis of pectinolytic enzymes by Aspergillus Niger [PDF]

open access: yes
The paper examines effects of different inorganic salts in an apple pulp base on the production of pectinolytic enzymes with the aim of optimizing the medium for maximal enzyme production.
Mojsov, Kiro
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The electrochemistry of redox enzymes [PDF]

open access: yes
The work presented in this thesis is of two types. Firstly methods for the electrochemical immobilisation of redox enzymes in organic polymers are described.
Whitaker, Richard George
core  

Immobilization of enzymes on magnetic particles

open access: yes, 2006
Item not available in this repository.Magnetic particles have been increasingly used as carriers for binding proteins, enzymes, and drugs. Such immobilization procedures for proteins, enzymes, antibodies, and other biologically active compounds have a ...
Michael Trevan   +20 more
core   +1 more source

Elucidation of the noncovalent interactions driving enzyme activity guides branching enzyme engineering for α-glucan modification

open access: yesNature Communications
Branching enzymes (BEs) confer to α-glucans, the primary energy-storage reservoir in nature, a variety of features, like slow digestion. The full catalytic cycle of BEs can be divided in six steps, namely two covalent catalytic steps involving ...
Zhiyou Zong   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Biomass Hydrolyzing Enzymes

open access: yes
Lignocellulosic biomass is the most abundant, ubiquitous polymer on Earth available to benefit mankind. Biomass biorefinery has taken center stage in the world’s economy and is becoming diverse with time.
Gurrani, Swapnil,   +6 more
core   +1 more source

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]

open access: yes, 2010
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
core  

Enzymes-Encapsulated Defective Metal–Organic Framework Hydrogel Coupling with a Smartphone for a Portable Glucose Biosensor

open access: yes
Enzymes featuring high catalytic efficiency and selectivity have been widely used as the sensing element in analytical chemistry. However, the structural fragility and poor machinability of an enzyme significantly limit its practicability in biosensors ...
Yujian Shen (13923476)   +7 more
core   +1 more source

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