Results 71 to 80 of about 2,028,343 (313)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Water availability affects extracellular hydrolytic enzyme production by Aspergillus flavus and Aspergillus parasiticus [PDF]

, 2009
The objectives of this study were to examine the effect of different water activities (a(w); 0.99, 0.96 and 0.94) and time (up to 120 h) on quantitative and specific enzyme production during germination and initial growth of Aspergillus flavus and A ...
Shah, Hamid Ullah, N. Magan, Magan, Naresh, S. Alam, Alam, Sahib, H. Shah   +5 more
core   +1 more source

Substrate Recognition Governs Reverse Transcriptase Resistance to Diagnostic Inhibitors in RT-qPCR

Diagnostics
Background: Reverse transcription is a key step in emerging RNA diagnostics, but reverse transcriptase (RT) enzymes often fail in the presence of inhibitors carried over from clinical samples or introduced during RNA extraction.
Inês F. Costa, Vânia O. Fernandes, Victor D. Alves, Virgínia M. R. Pires, Joana A. Brás, Pedro Bule, Carlos M. G. A. Fontes   +6 more
doaj   +1 more source

The Characterization and Modification of a Novel Bifunctional and Robust Alginate Lyase Derived from Marinimicrobium sp. H1

Marine Drugs, 2019
Alginase lyase is an important enzyme for the preparation of alginate oligosaccharides (AOS), that possess special biological activities and is widely used in various fields, such as medicine, food, and chemical industry.
Junjun Yan, Peng Chen, Yan Zeng, Yan Men, Shicheng Mu, Yueming Zhu, Yefu Chen, Yuanxia Sun   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Extracellular enzymes in bioremediation: potential and limitations

, 2016
Bioremediation processes often pivot on the activity of living organisms such as microorganisms, plants, algae. Bioremediation of contaminated soil and water finds very efficient tools in extracellular enzymes.
RAO, MARIA ANTONIETTA
core  

Biochemical Characterisation of Reconstructed Ancestral CM-DAH7PS Enzymes [PDF]

, 2012
Thermophily has been proposed to be a primitive trait (Stetter, 2006, Pace, 1991, Woese, 1987) which has led to suggestions that all contemporary thermophilic species are the direct descendants of ancient thermophilic organisms.
McMillan, Joel Patrick
core  

Ionic Liquids as (Co-)Solvents for Nonhydrolytic Enzymes

, 2012
Summary This chapter contains sections titled: Nomenclature of ILs Ionic Liquids and Nonhydrolytic Enzymes Use of ILs in Oxidoreductase-Catalyzed Enzymatic Reactions ILs in Lyase-Catalyzed Reactions Prospects ...
Daniela Gamenara, Gustavo Seoane, Pablo Domínguez de María, Seoane, Gustavo,, Gamenara, Daniela,, Saenz Mendez, Patricia,, Dominguez de Maria, Pablo,, Patricia Saenz Méndez   +7 more
core   +1 more source

X-ray structure and function studies of key enzymes for biomass conversion [PDF]

, 2013
The need for large enzyme quantities due to the difficult hydrolysis of recalcitrant polysaccharides is still a major barrier to economical biomass conversion for biofuel production.
Wu, Miao
core   +1 more source

N-Terminal Sequences of Signal Peptides Assuming Critical Roles in Expression of Heterologous Proteins in Bacillus subtilis

Microorganisms
The N-terminal sequences of proteins and their corresponding encoding sequences may play crucial roles in the heterologous expression. In this study, the secretory expression of alkaline pectin lyase APL in B.
Meijuan Zhang, Jie Zhen, Jia Teng, Xingya Zhao, Xiaoping Fu, Hui Song, Yeni Zhang, Hongchen Zheng, Wenqin Bai   +8 more
doaj   +1 more source