Results 61 to 70 of about 2,144,314 (302)

Purification and biochemical characterization of a novel thermostable protease from the oyster mushroom Pleurotus sajor-caju strain CTM10057 with industrial interest

BMC Biotechnology, 2019
Background Proteases are hydrolytic enzymes that catalyze peptide linkage cleavage reactions at the level of proteins and peptides with different degrees of specificity. This group draws the attention of industry.
Maroua Omrane Benmrad, Sondes Mechri, Nadia Zaraî Jaouadi, Mouna Ben Elhoul, Hatem Rekik, Sami Sayadi, Samir Bejar, Nabil Kechaou, Bassem Jaouadi   +8 more
doaj   +1 more source

Nature's therapy for COVID-19: Targeting the vital non-structural proteins (NSP) from SARS-CoV-2 with phytochemicals from Indian medicinal plants

Phytomedicine Plus, 2021
Background: Containing COVID-19 is still a global challenge. It has affected the ''normal'' world by targeting its economy and health sector. The effect is shifting of focus of research from life threatening diseases like cancer. Thus, we need to develop
Pratap Kumar Parida, Dipak Paul, Debamitra Chakravorty   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The redox-sensitive transcription factor Rap2.4a controls nuclear expression of 2-Cys peroxiredoxin A and other chloroplast antioxidant enzymes [PDF]

, 2008
Shaikhali J, Heiber I, Seidel T, et al. The redox-sensitive transcription factor Rap2.4a controls nuclear expression of 2-Cys peroxiredoxin A and other chloroplast antioxidant enzymes. BMC Plant Biology.
Thorsten Seidel, Birkmann Stefan, Hiltscher, Heiko, Baier Margarete, Shaikhali, Jehad, Birkmann, Stefan, Heiber Isabelle, Stroeher, Elke, Dietz Karl-Josef, Karl-Josef Dietz, Baier, Margarete, Margarete Baier, Heiber, Isabelle, Hiltscher Heiko, Shaikhali Jehad, Heiko Hiltscher, Dietz, Karl-Josef, Isabelle Heiber, Elke Ströher, Seidel Thorsten, Jehad Shaikhali, Seidel, Thorsten, Ströher Elke, Stefan Birkmann   +23 more
core   +1 more source

The phenomenon of degeneration of industrial Trichoderma reesei strains

Biotechnology for Biofuels, 2021
Background Even if the loss of production capacity of a microorganism is said to be a serious problem in various biotechnology industries, reports in literature are rather rare. Strains of the genera Trichoderma reesei are used for large-scale production
R. Martzy, T. M. Mello-de-Sousa, R. L. Mach, D. Yaver, A. R. Mach-Aigner   +4 more
doaj   +1 more source

The Interaction Efficiency of XPD-p44 With Bulky DNA Damages Depends on the Structure of the Damage

Frontiers in Cell and Developmental Biology, 2021
The successful elimination of bulky DNA damages via the nucleotide excision repair (NER) system is largely determined by the damage recognition step. This step consists of primary recognition and verification of the damage. The TFIIH helicase XPD plays a
Irina Petruseva, Natalia Naumenko, Jochen Kuper, Rashid Anarbaev, Jeannette Kappenberger, Caroline Kisker, Olga Lavrik   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cyanobacteria: A Promising Source of Antifungal Metabolites

Marine Drugs, 2023
Cyanobacteria are a rich source of secondary metabolites, and they have received a great deal of attention due to their applicability in different industrial sectors. Some of these substances are known for their notorious ability to inhibit fungal growth.
Samuel Cavalcante do Amaral, Luciana Pereira Xavier, Vítor Vasconcelos, Agenor Valadares Santos   +3 more
doaj   +1 more source