Results 11 to 20 of about 3,170,739 (359)

Enzymes [PDF]

British Journal of Pharmacology, 2007
ALEXANDER, S.P.H., MATHIE, A. & PETERS, J.A. (2007). Guide to Receptors and Channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol., 150 (Suppl. 1), S1–S168.
SPH Alexander, A Mathie, JA Peters
openaire   +4 more sources

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

Malaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika, Alida R. Harahap, Lydia V. Panggalo, Sri Widia A. Jusman, Ari W. Satyagraha   +4 more
doaj   +1 more source

Natural catalytic immunoglobulins hydrolyzing histones as a link between inflammation and humoral immunity in schizophrenia

European Psychiatry, 2021
Introduction Schizophrenia pathogenesis is known to be associated with chronic low-grade inflammation. Inflammation can be caused by extracellular histones that are released from cells due to apoptosis dysfunction.
E. Ermakov, V. Buneva, G. Nevinsky
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G, Cusumano, Zachary T, Flores-Mireles, Ana L, Hultgren, Scott J, Takagi, Enzo, Xu, Wei   +5 more
core   +3 more sources

Oncogenic BRCA1,2 Mutations in the Human Lineage—A By-Product of Sexual Selection?

Biomedicines, 2023
In this review, we discuss the long-known problem of tissue-specific carcinogenesis in BRCA1 and BRCA2 mutation carriers: while the genes are expressed ubiquitously, increased cancer risk is observed mostly in the breast and ovaries, and to a much lesser
Tatyana V. Korneenko, Nikolay B. Pestov
doaj   +1 more source

Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]

, 2015
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi, Arne Holmgren, Chan PH, Chen EP, Chu FF, Daiber A, Elias S. J. Arnér, Geismann C, Hogan B, Jaarsma D, Jian-Hong Zhu, Jin R, Leitzmann C, Li JJ, Li JJ, Lu YP, Makino N, Miranda-Vizuete A, Mirochnitchenko O, Motoori S, Mulder DW, Ogata M, Oury TD, Papaioannou V, Radi R, Sandbach JM, Takahara S, Thimmulappa RK, Tome ME, Vogel U, Wang F, Wen JK, Wen-Hsing Cheng, Wispe JR, Woychik RP, Xin Gen Lei, Ye-Shih Ho, Yongping Bao, Yoshida T   +38 more
core   +1 more source

Enzymatic functionalization of carbon-hydrogen bonds [PDF]

, 2011
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H., Coelho, Pedro S., Lewis, Jared C.   +2 more
core   +1 more source

Biosynthesis of dendroketose from different carbon sources using in vitro and in vivo metabolic engineering strategies

Biotechnology for Biofuels, 2018
Background Asymmetric aldol-type C–C bond formation with ketones used as electrophilic receptor remains a challenging reaction for aldolases as biocatalysts.
Jiangang Yang, Yueming Zhu, Ge Qu, Yan Zeng, Chaoyu Tian, Caixia Dong, Yan Men, Longhai Dai, Zhoutong Sun, Yuanxia Sun, Yanhe Ma   +10 more
doaj   +1 more source

Diamide-based screening method for the isolation of improved oxidative stress tolerance phenotypes in Bacillus mutant libraries

Microbiology Spectrum, 2023
The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve, Borja Ferrero-Bordera, Sandra Maaß, Dörte Becher, Ruth Schwerdtfeger, Jan Maarten van Dijl, Michael Seefried   +6 more
doaj   +1 more source

Enzyme localization can drastically affect signal amplification in signal transduction pathways [PDF]

, 2005
Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity.
van Albada, Siebe B., Wolde, Pieter Rein ten   +1 more
core   +5 more sources