Results 11 to 20 of about 3,216,786 (362)

Visual detection of isothermal nucleic acid amplification using pH-sensitive dyes

BioTechniques, 2015
Nucleic acid amplification is the basis for many molecular diagnostic assays. In these cases, the amplification product must be detected and analyzed, typically requiring extended workflow time, sophisticated equipment, or both.
Nathan A. Tanner, Yinhua Zhang, Thomas C. Evans   +2 more
doaj   +1 more source

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

Malaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika, Alida R. Harahap, Lydia V. Panggalo, Sri Widia A. Jusman, Ari W. Satyagraha   +4 more
doaj   +1 more source

Current Knowledge on Microviridin from Cyanobacteria

Marine Drugs, 2021
Cyanobacteria are a rich source of secondary metabolites with a vast biotechnological potential. These compounds have intrigued the scientific community due their uniqueness and diversity, which is guaranteed by a rich enzymatic apparatus.
Samuel Cavalcante do Amaral, Patrick Romano Monteiro, Joaquim da Silva Pinto Neto, Gustavo Marques Serra, Evonnildo Costa Gonçalves, Luciana Pereira Xavier, Agenor Valadares Santos   +6 more
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G, Cusumano, Zachary T, Flores-Mireles, Ana L, Hultgren, Scott J, Takagi, Enzo, Xu, Wei   +5 more
core   +3 more sources

Oncogenic BRCA1,2 Mutations in the Human Lineage—A By-Product of Sexual Selection?

Biomedicines, 2023
In this review, we discuss the long-known problem of tissue-specific carcinogenesis in BRCA1 and BRCA2 mutation carriers: while the genes are expressed ubiquitously, increased cancer risk is observed mostly in the breast and ovaries, and to a much lesser
Tatyana V. Korneenko, Nikolay B. Pestov
doaj   +1 more source

Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]

, 2015
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi, Arne Holmgren, Chan PH, Chen EP, Chu FF, Daiber A, Elias S. J. Arnér, Geismann C, Hogan B, Jaarsma D, Jian-Hong Zhu, Jin R, Leitzmann C, Li JJ, Li JJ, Lu YP, Makino N, Miranda-Vizuete A, Mirochnitchenko O, Motoori S, Mulder DW, Ogata M, Oury TD, Papaioannou V, Radi R, Sandbach JM, Takahara S, Thimmulappa RK, Tome ME, Vogel U, Wang F, Wen JK, Wen-Hsing Cheng, Wispe JR, Woychik RP, Xin Gen Lei, Ye-Shih Ho, Yongping Bao, Yoshida T   +38 more
core   +1 more source

Enzymatic functionalization of carbon-hydrogen bonds [PDF]

, 2011
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H., Coelho, Pedro S., Lewis, Jared C.   +2 more
core   +1 more source

Biosynthesis of dendroketose from different carbon sources using in vitro and in vivo metabolic engineering strategies

Biotechnology for Biofuels, 2018
Background Asymmetric aldol-type C–C bond formation with ketones used as electrophilic receptor remains a challenging reaction for aldolases as biocatalysts.
Jiangang Yang, Yueming Zhu, Ge Qu, Yan Zeng, Chaoyu Tian, Caixia Dong, Yan Men, Longhai Dai, Zhoutong Sun, Yuanxia Sun, Yanhe Ma   +10 more
doaj   +1 more source

Diamide-based screening method for the isolation of improved oxidative stress tolerance phenotypes in Bacillus mutant libraries

Microbiology Spectrum, 2023
The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve, Borja Ferrero-Bordera, Sandra Maaß, Dörte Becher, Ruth Schwerdtfeger, Jan Maarten van Dijl, Michael Seefried   +6 more
doaj   +1 more source

Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes [PDF]

, 2006
ISWI proteins form the catalytic core of a subset of ATP-dependent chromatin remodelling activities in eukaryotes from yeast to man. Many of these complexes have been found to reposition nucleosomes, but with different directionalities.
Alen, Beard, Becker, Brehm, Bruno, Bruno, Davey, Dillingham, Drew, Eberharter, Elfring, Fazzio, Flaus, Flaus, Flaus, Hamiche, Kagalwala, Kang, Kassabov, Langst, Lorch, Lowary, Luger, Lusser, Meersseman, Mizuguchi, Morillon, Rigaut, Schnitzler, Tran, Tsukiyama, Tsukiyama, Vary, Zofall   +33 more
core   +4 more sources