Results 21 to 30 of about 3,038,812 (378)

Ginsentide-like Coffeetides Isolated from Coffee Waste Are Cell-Penetrating and Metal-Binding Microproteins

open access: yesMolecules, 2023
Coffee processing generates a huge amount of waste that contains many natural products. Here, we report the discovery of a panel of novel cell-penetrating and metal ion-binding microproteins designated coffeetide cC1a–c and cL1–6 from the husk of two ...
James P. Tam   +4 more
doaj   +1 more source

Phoresis and Enhanced Diffusion Compete in Enzyme Chemotaxis [PDF]

open access: yesNano Lett. 2018, 18, 4, 2711-2717, 2021
Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for chemotaxis, valid for enzymes and other small molecules.
arxiv   +1 more source

Oncogenic BRCA1,2 Mutations in the Human Lineage—A By-Product of Sexual Selection?

open access: yesBiomedicines, 2023
In this review, we discuss the long-known problem of tissue-specific carcinogenesis in BRCA1 and BRCA2 mutation carriers: while the genes are expressed ubiquitously, increased cancer risk is observed mostly in the breast and ovaries, and to a much lesser
Tatyana V. Korneenko, Nikolay B. Pestov
doaj   +1 more source

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

open access: yesMalaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika   +4 more
doaj   +1 more source

Natural catalytic immunoglobulins hydrolyzing histones as a link between inflammation and humoral immunity in schizophrenia

open access: yesEuropean Psychiatry, 2021
Introduction Schizophrenia pathogenesis is known to be associated with chronic low-grade inflammation. Inflammation can be caused by extracellular histones that are released from cells due to apoptosis dysfunction.
E. Ermakov, V. Buneva, G. Nevinsky
doaj   +1 more source

Visual detection of isothermal nucleic acid amplification using pH-sensitive dyes

open access: yesBioTechniques, 2015
Nucleic acid amplification is the basis for many molecular diagnostic assays. In these cases, the amplification product must be detected and analyzed, typically requiring extended workflow time, sophisticated equipment, or both.
Nathan A. Tanner   +2 more
doaj   +1 more source

Current Knowledge on Microviridin from Cyanobacteria

open access: yesMarine Drugs, 2021
Cyanobacteria are a rich source of secondary metabolites with a vast biotechnological potential. These compounds have intrigued the scientific community due their uniqueness and diversity, which is guaranteed by a rich enzymatic apparatus.
Samuel Cavalcante do Amaral   +6 more
doaj   +1 more source

Diamide-based screening method for the isolation of improved oxidative stress tolerance phenotypes in Bacillus mutant libraries

open access: yesMicrobiology Spectrum, 2023
The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve   +6 more
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

open access: yes, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G   +5 more
core   +3 more sources

Biotransformation of explosives by the old yellow enzyme family of flavoproteins [PDF]

open access: yes, 2004
Several independent studies of bacterial degradation of nitrate ester explosives have demonstrated the involvement of flavin-dependent oxidoreductases related to the old yellow enzyme (OYE) of yeast. Some of these enzymes also transform the nitroaromatic
Bruce, N.C.   +3 more
core   +2 more sources

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