Results 1 to 10 of about 198,261 (297)

Effect of Dupilumab on Blood Eosinophil Counts in Patients With Asthma, Chronic Rhinosinusitis With Nasal Polyps, Atopic Dermatitis, or Eosinophilic Esophagitis.

open access: yesJournal of Allergy and Clinical Immunology: In Practice, 2022
BACKGROUND Transient increases in blood eosinophil counts have been observed in dupilumab clinical trials. OBJECTIVE Assessment of eosinophil counts and eosinophilia-related treatment-emergent adverse events (TEAEs) across 11 dupilumab clinical trials,
M. Wechsler   +16 more
semanticscholar   +1 more source

Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts

open access: yesBiomedicines, 2022
Higher blood and sputum eosinophil counts are associated with a greater response to corticosteroids in COPD. Low blood eosinophil counts exhibit greater stability over time whereas higher counts demonstrate more variability.
Augusta Beech   +2 more
doaj   +1 more source

Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies.

open access: yesAnnual Review of Immunology, 2021
The enigmatic eosinophil has emerged as an exciting component of the immune system, involved in a plethora of homeostatic and inflammatory responses. Substantial progress has been achieved through experimental systems manipulating eosinophils in vivo ...
E. Jacobsen   +8 more
semanticscholar   +1 more source

Haematological Predictors of Section Recovery in Dengue Cases [PDF]

open access: yesNational Journal of Laboratory Medicine, 2019
Introduction: Dengue fever is associated with relative increase in haemoglobin, haematocrit and monocyte counts and reduction in platelet counts, eosinophil percentage and absolute eosinophil count.
Sushma Nayar   +2 more
doaj   +1 more source

Patients of COVID-19 may benefit from sustained Lopinavir-combined regimen and the increase of Eosinophil may predict the outcome of COVID-19 progression

open access: yesInternational Journal of Infectious Diseases, 2020
Highlights • An asymptomatic 2019-coronavirus disease patient with normal radiography throughout appeared in this study.• Lopinavir has a positive effect on 2019-coronavirus disease patients.• Eosinophil counts presented potentiality as a predictor on ...
Fang Liu   +7 more
semanticscholar   +1 more source

Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. [PDF]

open access: yesPLoS ONE, 2013
MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels.
Thomas X Lu   +9 more
doaj   +1 more source

Eosinophil responses during COVID-19 infections and coronavirus vaccination

open access: yesJournal of Allergy and Clinical Immunology, 2020
Eosinophils are circulating and tissue-resident leukocytes that have potent pro-inflammatory effects in a number of diseases. Recently, eosinophils have been shown to have a variety of other functions, including immunoregulation and antiviral activity ...
Andrew W. Lindsley   +2 more
semanticscholar   +1 more source

Blood eosinophil count in the general population: typical values and potential confounders

open access: yesEuropean Respiratory Journal, 2020
There is growing interest in blood eosinophil counts in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).
S. Hartl   +9 more
semanticscholar   +1 more source

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis [PDF]

open access: yesKorean Journal of Pediatrics, 2019
Background Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic ...
Yeonu Choi   +4 more
doaj   +1 more source

Clinical and Biological Markers in Hypereosinophilic Syndromes

open access: yesFrontiers in Medicine, 2017
Hypereosinophilic syndromes (HES) are rare, heterogeneous syndromes characterized by markedly elevated eosinophil counts in the blood and/or tissue and evidence of eosinophil-associated pathology. Although parasitic infections, drug hypersensitivity, and
Paneez Khoury   +2 more
doaj   +1 more source

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