Results 1 to 10 of about 77,673 (236)

Transcription Factors in Eosinophil Development and As Therapeutic Targets

open access: yesFrontiers in Medicine, 2017
Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor
Patricia C. Fulkerson
exaly   +3 more sources

Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts

open access: yesBiomedicines, 2022
Higher blood and sputum eosinophil counts are associated with a greater response to corticosteroids in COPD. Low blood eosinophil counts exhibit greater stability over time whereas higher counts demonstrate more variability.
Augusta Beech   +2 more
doaj   +1 more source

Eosinophils in eosinophilic pneumonia [PDF]

open access: yesEuropean Respiratory Journal, 1996
Idiopathic eosinophilic pneumonia (IEP) is an uncom-mon disease of unknown aetiology characterized by theaccumulation of eosinophils in the lung, variable bloodeosinophilia and peripheral opacities on the chest radio-gram. The response to steroid treatment is dramatic butrelapses are frequent, requiring the use of long-termsteroid treatment [1 ...
ALBERA, Carlo, P. GHIO
openaire   +2 more sources

Haematological Predictors of Section Recovery in Dengue Cases [PDF]

open access: yesNational Journal of Laboratory Medicine, 2019
Introduction: Dengue fever is associated with relative increase in haemoglobin, haematocrit and monocyte counts and reduction in platelet counts, eosinophil percentage and absolute eosinophil count.
Sushma Nayar   +2 more
doaj   +1 more source

Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. [PDF]

open access: yesPLoS ONE, 2013
MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels.
Thomas X Lu   +9 more
doaj   +1 more source

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis [PDF]

open access: yesKorean Journal of Pediatrics, 2019
Background Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic ...
Yeonu Choi   +4 more
doaj   +1 more source

Dermatomyositis with Eosinophils [PDF]

open access: yesDermatopathology, 2023
Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin, and a predominantly lymphocytic infiltrate.
Isabella I. Sanchez   +4 more
openaire   +3 more sources

Clinical and Biological Markers in Hypereosinophilic Syndromes

open access: yesFrontiers in Medicine, 2017
Hypereosinophilic syndromes (HES) are rare, heterogeneous syndromes characterized by markedly elevated eosinophil counts in the blood and/or tissue and evidence of eosinophil-associated pathology. Although parasitic infections, drug hypersensitivity, and
Paneez Khoury   +2 more
doaj   +1 more source

A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]

open access: yes, 1993
Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR   +3 more
core   +1 more source

Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide

open access: yesCancer Medicine, 2020
Lenalidomide is an immunomodulatory drug that is administered commonly in patients with relapsed or refractory multiple myeloma (RRMM). Eosinophils have immunological functions, for instance, in allergic diseases and asthma. The purpose of this study was
Kazuhito Suzuki   +5 more
doaj   +1 more source

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