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Nonlinear association between blood eosinophil counts and clinical outcomes in ICU-Admitted patients with acute exacerbation of COPD: a retrospective observational study [PDF]

open access: yesBMC Pulmonary Medicine
Background This retrospective cohort study aimed to examine the association between blood eosinophil counts and in-hospital mortality among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to the intensive care ...
Rundi Gao   +4 more
doaj   +2 more sources

Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies.

open access: yesAnnual Review of Immunology, 2021
The enigmatic eosinophil has emerged as an exciting component of the immune system, involved in a plethora of homeostatic and inflammatory responses. Substantial progress has been achieved through experimental systems manipulating eosinophils in vivo ...
E. Jacobsen   +8 more
semanticscholar   +1 more source

Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts

open access: yesBiomedicines, 2022
Higher blood and sputum eosinophil counts are associated with a greater response to corticosteroids in COPD. Low blood eosinophil counts exhibit greater stability over time whereas higher counts demonstrate more variability.
Augusta Beech   +2 more
doaj   +1 more source

Haematological Predictors of Section Recovery in Dengue Cases [PDF]

open access: yesNational Journal of Laboratory Medicine, 2019
Introduction: Dengue fever is associated with relative increase in haemoglobin, haematocrit and monocyte counts and reduction in platelet counts, eosinophil percentage and absolute eosinophil count.
Sushma Nayar   +2 more
doaj   +1 more source

Blood eosinophil count in the general population: typical values and potential confounders

open access: yesEuropean Respiratory Journal, 2020
There is growing interest in blood eosinophil counts in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).
S. Hartl   +9 more
semanticscholar   +1 more source

Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. [PDF]

open access: yesPLoS ONE, 2013
MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels.
Thomas X Lu   +9 more
doaj   +1 more source

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis [PDF]

open access: yesKorean Journal of Pediatrics, 2019
Background Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic ...
Yeonu Choi   +4 more
doaj   +1 more source

Clinical and Biological Markers in Hypereosinophilic Syndromes

open access: yesFrontiers in Medicine, 2017
Hypereosinophilic syndromes (HES) are rare, heterogeneous syndromes characterized by markedly elevated eosinophil counts in the blood and/or tissue and evidence of eosinophil-associated pathology. Although parasitic infections, drug hypersensitivity, and
Paneez Khoury   +2 more
doaj   +1 more source

Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide

open access: yesCancer Medicine, 2020
Lenalidomide is an immunomodulatory drug that is administered commonly in patients with relapsed or refractory multiple myeloma (RRMM). Eosinophils have immunological functions, for instance, in allergic diseases and asthma. The purpose of this study was
Kazuhito Suzuki   +5 more
doaj   +1 more source

Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study

open access: yesScientific Reports, 2021
Blood eosinophil count is a useful measure in asthma or COPD management. Recent epidemiological studies revealed that body mass index (BMI) is positively associated with eosinophil counts.
Kenta Nishi   +17 more
doaj   +1 more source

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