Results 1 to 10 of about 202,796 (424)

Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies

open access: yesAnnual Review of Immunology, 2021
The enigmatic eosinophil has emerged as an exciting component of the immune system, involved in a plethora of homeostatic and inflammatory responses. Substantial progress has been achieved through experimental systems manipulating eosinophils in vivo ...
Elizabeth A Jacobsen   +2 more
exaly   +2 more sources

The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease

open access: yesFrontiers in Medicine, 2018
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
Kyle T Amber   +2 more
exaly   +2 more sources

Transcription Factors in Eosinophil Development and As Therapeutic Targets

open access: yesFrontiers in Medicine, 2017
Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor
Patricia C. Fulkerson
exaly   +3 more sources

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation [PDF]

open access: yesJournal of Experimental Medicine, 1994
Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Airways Inflammation   +9 more
semanticscholar   +3 more sources

Eosinophil Secretion of Granule-Derived Cytokines

open access: yesFrontiers in Immunology, 2014
Eosinophils are tissue-dwelling leukocytes, present in the thymus, and gastrointestinal and genitourinary tracts of healthy individuals at baseline, and recruited, often in large numbers, to allergic inflammatory foci and sites of active tissue repair ...
Lisa A Spencer   +2 more
exaly   +2 more sources

Impact of blood eosinophil count on clinical outcomes in hospitalized Syrian patients with COPD exacerbation. [PDF]

open access: yesJ Int Med Res
Objective In this multicenter retrospective study, we evaluated the prognostic role of blood eosinophil count on clinical outcomes in hospitalized patients with exacerbations of chronic obstructive pulmonary disease (COPD).
Albuaini S   +3 more
europepmc   +2 more sources

Type 2 innate lymphoid cells control eosinophil homeostasis

open access: yesNature, 2013
Richard M Locksley   +2 more
exaly   +2 more sources

Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts

open access: yesBiomedicines, 2022
Higher blood and sputum eosinophil counts are associated with a greater response to corticosteroids in COPD. Low blood eosinophil counts exhibit greater stability over time whereas higher counts demonstrate more variability.
Augusta Beech   +2 more
doaj   +1 more source

Haematological Predictors of Section Recovery in Dengue Cases [PDF]

open access: yesNational Journal of Laboratory Medicine, 2019
Introduction: Dengue fever is associated with relative increase in haemoglobin, haematocrit and monocyte counts and reduction in platelet counts, eosinophil percentage and absolute eosinophil count.
Sushma Nayar   +2 more
doaj   +1 more source

Blood eosinophil count in the general population: typical values and potential confounders

open access: yesEuropean Respiratory Journal, 2020
There is growing interest in blood eosinophil counts in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).
S. Hartl   +9 more
semanticscholar   +1 more source

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