Results 91 to 100 of about 186,812 (342)

Eosinophilic gastroenteritis

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 2014
The eosinophilic gastroenteritis is a disease of unknown etiopathogenesis and rare presentation, with several clinical symptoms, ranging from mild episodes until nonspecific abdominal acute episodes of intestinal obstruction, which some times make it necessary urgent surgical treatment.
Ondina Marlene Garibay-Vargas, Diego Soto-Candia, Erika Coria-Ramírez, María Isabel Castrejón-Vázquez, María Eugenia Vargas-Camaño, Gabriel Ramos-Acosta, Moisés Salamanca-García, Ricardo Leopoldo Guido-Bayardo   +7 more
openaire   +2 more sources

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

Eosinophil Secretion of Granule-Derived Cytokines

Frontiers in Immunology, 2014
Eosinophils are tissue-dwelling leukocytes, present in the thymus, and gastrointestinal and genitourinary tracts of healthy individuals at baseline, and recruited, often in large numbers, to allergic inflammatory foci and sites of active tissue repair ...
L. Spencer, Kennedy Bonjour, R. Melo, P. Weller   +3 more
semanticscholar   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Association of Pretreatment Neutrophil-to-Eosinophil Ratio with Clinical Outcomes in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Treated with Nivolumab

Cancer Management and Research, 2022
Shinsuke Suzuki, Tomoe Abe, Tentaro Endo, Haruka Kaya, Takuro Kitabayashi, Yohei Kawasaki, Takechiyo Yamada Department of Otorhinolaryngology & Head and Neck Surgery, Akita University Graduate School of Medicine, Akita, 010-8543, JapanCorrespondence ...
Suzuki S, Abe T, Endo T, Kaya H, Kitabayashi T, Kawasaki Y, Yamada T   +6 more
doaj  

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Evaluation of Eosinophilic Inflammation in a Novel Murine Atopic Keratoconjunctivitis Model Induced by Crude Dermatophagoides farinae Antigen

Allergology International, 2012
Background: The purpose of this study is to conduct a histopathological research of the conjunctival findings and eosinophilic inflammation of novel atopic keratoconjunctivitis in a NC/Nga mouse model using crude Dermatophagoides farina.
Yusuke Hara, Jun Shoji, Shinsuke Hori, Akiko Ishimori, Hiroshi Kato, Noriko Inada, Mitsuru Sawa   +6 more
doaj   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Phloretin Attenuates Allergic Airway Inflammation and Oxidative Stress in Asthmatic Mice

Frontiers in Immunology, 2017
Phloretin (PT), isolated from the apple tree, was previously demonstrated to have antioxidative and anti-inflammatory effects in macrophages and anti-adiposity effects in adipocytes.
Wen-Chung Huang, Wen-Chung Huang, Li-Wen Fang, Chian-Jiun Liou, Chian-Jiun Liou   +4 more
doaj   +1 more source